Jeffrey L. Larson

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index1.8kcitations33works0.02yr avg
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Research Topics

Carcinogens and Genotoxicity Assessment(7), Influenza Virus Research Studies(6), Respiratory viral infections research(5), RNA and protein synthesis mechanisms(3), Microbial Natural Products and Biosynthesis(2)

Publications33 total

Preclinical efficacy of the Wnt/β-catenin pathway inhibitor BC2059 for the treatment of desmoid tumors
PLoS ONE·2022· 19 citedOpen Access
Tegavivint and the β-Catenin/ALDH Axis in Chemotherapy-Resistant and Metastatic Osteosarcoma
JNCI Journal of the National Cancer Institute·2019· 98 citedOpen Access
Toxicity Evaluations, ICH Guidelines, and Current Practice
2016
A Safety Evaluation of DAS181, a Sialidase Fusion Protein, in Rodents
Toxicological Sciences·2011· 17 citedOpen Access
Phenotypic and genotypic characterization of influenza virus mutants selected with the sialidase fusion protein DAS181
Journal of Antimicrobial Chemotherapy·2010· 51 citedOpen Access
Antiviral Strategies for Pandemic and Seasonal Influenza
Viruses·2010· 12 citedOpen Access
Sialidase‐Based Anti–Influenza Virus Therapy Protects against Secondary Pneumococcal Infection
The Journal of Infectious Diseases·2010· 43 citedOpen Access
Novel Pandemic Influenza A(H1N1) Viruses Are Potently Inhibited by DAS181, a Sialidase Fusion Protein
PLoS ONE·2009· 107 citedOpen Access
Inhibition of Neuraminidase Inhibitor-Resistant Influenza Virus by DAS181, a Novel Sialidase Fusion Protein
PLoS ONE·2009· 77 citedOpen Access
Antiretroviral Activity of the Anti‐CD4 Monoclonal Antibody TNX‐355 in Patients Infected with HIV Type 1
The Journal of Infectious Diseases·2004· 193 cited
Chronic Effects of the Novel Glucocorticosteroid RPR 106541 Administered to Beagle Dogs by Inhalation
Toxicologic Pathology·2000· 14 cited
The Reproductive and Developmental Toxicity of the Antifungal Drug Nyotran(R) (Liposomal Nystatin) in Rats and Rabbits
Toxicological Sciences·2000· 31 cited
Toxicologic and Carcinogenic Effects of the Type IV Phosphodiesterase Inhibitor RP 73401 on the Nasal Olfactory Tissue in Rats
Toxicologic Pathology·1999· 27 cited
Levels of myc, fos, Ha-ras, met and hepatocyte growth factor mRNA during regenerative cell proliferation in female mouse liver and male rat kidney after a cytotoxic dose of chloroform
Cancer Letters·1996· 8 cited
A 90-Day Chloroform Inhalation Study in Female and Male B6C3F<sub>1</sub> Mice: Implications for Cancer Risk Assessment
Toxicological Sciences·1996· 43 citedOpen Access
A 90-Day Chloroform Inhalation Study in F-344 Rats: Profile of Toxicity and Relevance to Cancer Studies
Toxicological Sciences·1996· 4 cited
A non-bile duct origin for intestinal crypt-like ducts with periductular fibrosis induced in livers of F344 rats by chloroform inhalation
Carcinogenesis·1996· 13 citedOpen Access
The Toxicity of Repeated Exposures to Rolipram, a Type IV Phosphodiesterase Inhibitor, in Rats
Pharmacology & Toxicology·1996· 74 cited
Toxicity and cell proliferation in the liver, kidneys and nasal passages of female F-344 rats, induced by chloroform administered by gavage
Food and Chemical Toxicology·1995· 44 cited
Induced regenerative cell proliferation in livers and kidneys of male F-344 rats given chloroform in corn oil by gavage or ad libitum in drinking water
Toxicology·1995· 48 cited
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Frequent Co-authors

Byron E. Butterworth(10), Douglas C. Wolf(9), Maria Hedlund(6), Fang Fang(6), Richard J. Bull(5), Kevin T. Morgan(5), Gallen Triana‐Baltzer(3), Michael V. Pino(3), Laura Aschenbrenner(3), Ruolan Han(2), Scott E. Fishman(2), Karen L. Cox(2), Eugene T. Seno(2), Charles L. Hershberger(2), Lee E. Geiger(2), Stéphane Mery(2), R. Harden(2), Kellie Jensen(2), MICHAEL V. TEMPLIN(2), KEITH C. JAMISON(2)