J. Margaret Hughes

Orange County Research Center — United States

Medicine · Health Sciences

21h-index1.8kcitations46works2.72yr avg
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Research Topics

Asthma and respiratory diseases(24), Immune Response and Inflammation(7), Mast cells and histamine(6), Cytokine Signaling Pathways and Interactions(6), Immune Cell Function and Interaction(5)

Publications46 total

Evaluating urinary metabolic profiles with wildland-urban-interface (wui) fire exposure among male firefighters: a comparison with municipal structure fires (msf)
Environmental Health·2025· 1 citedOpen Access
Changes in Serum Proteins in Firefighters Responding to the 2025 Los Angeles Urban Conflagrations
Journal of Occupational and Environmental Medicine·2025Open Access
Per- and polyfluoroalkyl substances (PFAS) and microRNA: An epigenome-wide association study in firefighters
Environmental Research·2025· 4 citedOpen Access
The Fire Fighter Cancer Cohort Study: Protocol for a Longitudinal Occupational Cohort Study
JMIR Research Protocols·2025· 4 citedOpen Access
The Fire Fighter Cancer Cohort Study: Protocol for a Longitudinal Occupational Cohort Study (Preprint)
2024Open Access
Firefighting, per‐ and polyfluoroalkyl substances, and DNA methylation of genes associated with prostate cancer risk
Environmental and Molecular Mutagenesis·2024· 7 citedOpen Access
Per- and Polyfluoroalkyl Substances, Epigenetic Age and DNA Methylation: A Cross-Sectional Study of Firefighters
Epigenomics·2021· 52 citedOpen Access
Differential DNA Methylation by Hispanic Ethnicity Among Firefighters in the United States
Epigenetics Insights·2021· 20 citedOpen Access
A Total Worker Health Approach to Skin Exposure Assessment: Experiences from the Firefighter Cancer Initiative
Annals of Work Exposures and Health·2020· 8 citedOpen Access
Information for CME Credit—Prevalence and Correlates of Receiving Medical Advice to Increase Physical Activity in U.S. Adults: National Health and Nutrition Examination Survey 2013–2016
American Journal of Preventive Medicine·2019Open Access
<scp>CXCL</scp>1 is a negative regulator of mast cell chemotaxis to airway smooth muscle cell products <i>in vitro</i>
Clinical & Experimental Allergy·2013· 18 cited
The HMGB1-RAGE axis is critical in the process of allergic sensitization
2013
Human lung mast cells alter asthmatic airway epithelial cell function
2013
Mast Cells Produce Novel Shorter Forms of Perlecan That Contain Functional Endorepellin
Journal of Biological Chemistry·2012· 68 citedOpen Access
Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL10: in vitro comparison with current asthma therapies
Respiratory Research·2012· 11 citedOpen Access
The effects of human lung mast cell products on the synthetic functions of lung fibroblasts
2012
Dimethylfumarate inhibits CXCL10<i>via</i>haem oxygenase-1 in airway smooth muscle
European Respiratory Journal·2012· 11 citedOpen Access
RAGE: a new frontier in chronic airways disease
British Journal of Pharmacology·2012· 99 citedOpen Access
Asthmatic airway smooth muscle CXCL10 production: mitogen-activated protein kinase JNK involvement
American Journal of Physiology-Lung Cellular and Molecular Physiology·2012· 51 citedOpen Access
TLR2 ligand engagement upregulates airway smooth muscle TNFα-induced cytokine production
American Journal of Physiology-Lung Cellular and Molecular Physiology·2012· 25 cited
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Frequent Co-authors

Carol Armour(22), Hatem Alkhouri(12), Alaina J. Ammit(8), Jaclyn M. Goodrich(8), Shawn C. Beitel(8), John Gulotta(8), Jefferey L. Burgess(8), Janette K. Burgess(7), Miriam M. Calkins(7), Qi Ge(6), Alberto J. Caban‐Martinez(6), Melissa Furlong(6), Maria B. Sukkar(5), Judith L. Black(5), Brian G. Oliver(5), Judith M. Graber(5), Sheridan Henness(4), Casey Grant(4), Anita E. Blake(4), Derek J. Urwin(4)