Michael J. Klemsz

Indiana University School of Medicine

Immunology and Microbiology · Life Sciences

24h-index3.2kcitations40works0.02yr avg
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Research Topics

Immune Cell Function and Interaction(8), T-cell and B-cell Immunology(6), Genomics and Chromatin Dynamics(6), Immune Response and Inflammation(5), Cytokine Signaling Pathways and Interactions(5)

Publications40 total

Inhibition of MEK signaling prevents SARS‐CoV2‐induced lung damage and improves the survival of infected mice
Journal of Medical Virology·2022· 15 citedOpen Access
Osteoclast-mediated bone loss observed in a COVID-19 mouse model
PMC·2022· 5 cited
Osteoclast-mediated bone loss observed in a COVID-19 mouse model
Bone·2021· 56 citedOpen Access
Oral immunotherapy with type V collagen in idiopathic pulmonary fibrosis
European Respiratory Journal·2015· 69 citedOpen Access
A Phase One, Open Label, Multi-Dose Study To Evaluate The Safety, Tolerability, And Biologic Effects Of Three Doses Of IW001 In Patients With Idiopathic Pulmonary Fibrosis (IPF)
2012
Pillars article: the macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene. Cell, 1990. 61: 113-124.
PubMed·2008· 2 cited
Vaccinia Virus Blocks Stat1-Dependent and Stat1-Independent Gene Expression Induced by Type I and Type II Interferons
Journal of Interferon & Cytokine Research·2008· 83 citedOpen Access
Poxvirus phosphatase alters interferon gamma regulated gene expression in macrophages
The FASEB Journal·2006
Histone H4 HDAC activity is necessary for expression of the PU.1 gene
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression·2005· 11 cited
PU.1 Expression Delineates Heterogeneity in Primary Th2 Cells
Immunity·2005· 154 citedOpen Access
Human papillomavirus type 16 E7 protein increases acetylation of histone H3 in human foreskin keratinocytes
Virology·2004· 44 cited
Cutting Edge: Induction of the Antigen-Processing Enzyme IFN-γ-Inducible Lysosomal Thiol Reductase in Melanoma Cells Is STAT1-Dependent but CIITA-Independent
The Journal of Immunology·2004· 66 citedOpen Access
Cathepsin E: A Novel Target for Regulation by Class II Transactivator
The Journal of Immunology·2004· 53 citedOpen Access
p38 activation through Toll-like receptors modulates IFN-γ-induced expression of the Tap-1 gene only in macrophages
Journal of Leukocyte Biology·2003· 9 cited
PU.1 regulates glutathione peroxidase expression in neutrophils
Journal of Leukocyte Biology·2003· 19 cited
Regulation of the PU.1 gene by distal elements
Blood·2001· 110 citedOpen Access
Loss of PU.1 Expression Following Inhibition of Histone Deacetylases
The Journal of Immunology·2001· 65 citedOpen Access
PU.1 Is a Lineage-specific Regulator of Tyrosine Phosphatase CD45
Journal of Biological Chemistry·2001· 29 citedOpen Access
Synergistic Induction of the Tap-1 Gene by IFN-γ and Lipopolysaccharide in Macrophages Is Regulated by STAT1
The Journal of Immunology·2000· 50 citedOpen Access
DNA Methylation and Chromatin Structure Regulate PU.1 Expression
DNA and Cell Biology·1999· 44 cited
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Frequent Co-authors

Richard A. Maki(14), Scott R. McKercher(11), Robert Hromas(6), Frédéric Pio(5), Chao‐Zhou Ni(5), Kathryn R. Ely(5), Antonio Celada(4), R. Kodandapani(4), R. Nicholas Laribee(4), Mark H. Kaplan(4), Charles Van Beveren(3), Edward F. Srour(3), Melissa A. Kacena(3), Gennaro Piccialli(2), Dawei Xu(2), Roger B. Slee(2), Daniel G. Tenen(2), Ping Li(2), William Shepard(2), David S. Wilkes(2)