Guanshan Zhu

Medicine · Health Sciences

30h-index4.3kcitations93works4.52yr avg
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Research Topics

Lung Cancer Treatments and Mutations(36), Cancer Genomics and Diagnostics(20), Colorectal Cancer Treatments and Studies(13), Fibroblast Growth Factor Research(12), RNA modifications and cancer(10)

Publications90 total

Clinical validation of a sensitive real-time PCR assay for detecting EGFR mutations in plasma ctDNA from patients with non-small cell lung cancer
2018
Detection of EGFR mutations in plasma circulating tumour DNA as a selection criterion for first-line gefitinib treatment in patients with advanced lung adenocarcinoma (BENEFIT): a phase 2, single-arm, multicentre clinical trial
The Lancet Respiratory Medicine·2018· 214 cited
Potential Resistance Mechanisms Revealed by Targeted Sequencing from Lung Adenocarcinoma Patients with Primary Resistance to Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors (TKIs)
Journal of Thoracic Oncology·2017· 59 citedOpen Access
Droplet digital PCR improved the EGFR mutation diagnosis with pleural fluid samples in non-small-cell lung cancer patients
Clinica Chimica Acta·2017· 25 cited
A consensus on liquid biopsy from the 2016 Chinese Lung Cancer Summit expert panel
ESMO Open·2017· 3 citedOpen Access
EGFR mutation status of paired cerebrospinal fluid and plasma samples in EGFR mutant non-small cell lung cancer with leptomeningeal metastases
Cancer Chemotherapy and Pharmacology·2016· 53 cited
Genome landscape of HCC and related HBV.
Figshare·2015Open Access
Abstract 4909: Increased IR-A/IR-B ratio in non-small cell lung cancers associates with lower epithelial-mesenchymal transition signature and longer survival in squamous cell lung carcinoma
Cancer Research·2015
Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinoma
BMC Cancer·2015· 30 citedOpen Access
Association of plasma EGFR T790M ctDNA status with clinical outcome in advanced NSCLC patients with acquired EGFR-TKI resistance.
Journal of Clinical Oncology·2015· 1 cited
Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma
PLoS ONE·2015· 65 citedOpen Access
Oncogenic HER2 fusions in gastric cancer
Journal of Translational Medicine·2015· 26 citedOpen Access
Highly Sensitive Droplet Digital PCR Method for Detection of EGFR-Activating Mutations in Plasma Cell–Free DNA from Patients with Advanced Non–Small Cell Lung Cancer
Journal of Molecular Diagnostics·2015· 197 citedOpen Access
Recurrent amplification of MYC and TNFRSF11B in 8q24 is associated with poor survival in patients with gastric cancer
Gastric Cancer·2015· 60 citedOpen Access
An evaluation and recommendation of the optimal methodologies to detect <i>RET</i> gene rearrangements in papillary thyroid carcinoma
Genes Chromosomes and Cancer·2014· 18 cited
Abstract 2923: Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinoma
Cancer Research·2014· 1 cited
Whole genome gene copy number profiling of gastric cancer identifies <i>PAK1</i> and <i>KRAS</i> gene amplification as therapy targets
Genes Chromosomes and Cancer·2014· 73 cited
EGFR mutation status in cerebrospinal fluid of NSCLC patients who developed leptomeningeal metastasis after EGFR-TKI treatment.
Journal of Clinical Oncology·2014· 2 cited
Noninvasive monitoring of dynamics of acquired EGFR-T790M mutation and discovery of its heterogeneity in patients with advanced NSCLC treated with EGFR-TKI.
Journal of Clinical Oncology·2014
Malignant Pleural Effusion Supernatants Are Substitutes for Metastatic Pleural Tumor Tissues in EGFR Mutation Test in Patients with Advanced Lung Adenocarcinoma
PLoS ONE·2014· 45 citedOpen Access
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Frequent Co-authors

Qunsheng Ji(12), Xiaolu Yin(9), David Goldman(7), Xinying Su(7), Zhongzheng Zhu(7), Zhengwei Dong(6), Ziliang Qian(6), Yachao Lu(6), Robert H. Lipsky(5), Xin Ye(5), Paul R. Gavine(5), Matti Virkkunen(4), Li Liang(4), Jingchuan Zhang(4), Liang Xie(4), Yun Sun(4), Zhong-Zheng Zhu(4), Wen‐Ming Cong(4), Longina A. Akhtar(3), Julie Taubman(3)