Kathryn Chapman

Veterinary · Health Sciences

34h-index3.9kcitations100works8.02yr avg
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Research Topics

Animal testing and alternatives(24), Computational Drug Discovery Methods(13), Biosimilars and Bioanalytical Methods(10), Monoclonal and Polyclonal Antibodies Research(9), Receptor Mechanisms and Signaling(7)

Publications99 total

Structural basis of Fanconi anemia pathway activation by FANCM
The EMBO Journal·2025· 8 citedOpen Access
Correction: Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking
Acta Neuropathologica Communications·2023Open Access
Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking
Acta Neuropathologica Communications·2023· 11 citedOpen Access
Differential Effects of Mutations of Popeye Domain Containing Proteins on Heteromeric Interaction and Membrane Trafficking
2022Open Access
Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer
Science Translational Medicine·2021· 34 citedOpen Access
Identification of SARS-CoV-2–induced pathways reveals drug repurposing strategies
Science Advances·2021· 57 citedOpen Access
Preclinical trial of a MAP4K4 inhibitor to reduce infarct size in the pig: does cardioprotection in human stem cell-derived myocytes predict success in large mammals?
Basic Research in Cardiology·2021· 27 citedOpen Access
Current and prospective computational approaches and challenges for developing COVID-19 vaccines
Advanced Drug Delivery Reviews·2021· 47 citedOpen Access
Logic-Guided Neural Utterance Generation from Drone Sensory Data (Extended Abstract).
Description Logics·2021
IKKε and TBK1 in diffuse large B‐cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF‐κB and IL‐10 signalling
Journal of Cellular and Molecular Medicine·2020· 9 citedOpen Access
Identification of SARS-CoV-2 induced pathways reveal drug repurposing strategies
2020· 2 citedOpen Access
Releasing the technical ‘shackles’ on GPCR drug discovery: opportunities enabled by detergent-free polymer lipid particle (PoLiPa) purification
Drug Discovery Today·2020· 14 cited
Selective protection of human cardiomyocytes from anthracycline cardiotoxicity by small molecule inhibitors of MAP4K4
Scientific Reports·2020· 34 citedOpen Access
MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo
Cell stem cell·2020· 11 citedOpen Access
CoLi at UdS at SemEval-2020 Task 12: Offensive Tweet Detection with Ensembling
2020· 1 citedOpen Access
MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo
Cell stem cell·2019· 106 citedOpen Access
Referee report. For: Insights into pancreatic β cell energy metabolism using rodent β cell models [version 2; referees: 1 approved, 1 approved with reservations, 1 not approved]
Faculty of 1000 Research Ltd·2019Open Access
Referee report. For: Insights into pancreatic β cell energy metabolism using rodent β cell models [version 3; peer review: 2 approved, 1 not approved]
Faculty of 1000 Research Ltd·2019Open Access
Abstract 3877: MPL-5821, a macrophage targeted ESMTM p38 MAPK inhibitor, inhibits the production of TLR agonist induced IL-10 whilst sparing T-cell functionality
Cancer Research·2018· 2 cited
Pharmacological validation of individual animal locomotion, temperature and behavioural analysis in group-housed rats using a novel automated home cage analysis system: A comparison with the modified Irwin test
Journal of Pharmacological and Toxicological Methods·2018· 21 citedOpen Access
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Frequent Co-authors

Sally Robinson(7), Michael D. Briggs(6), Fiona Sewell(5), Ian Ragan(5), Geert Mortier(4), Jessica A. Couch(4), Nick Pullen(4), Trevor R. Perrior(4), Paul Baldrick(4), Stuart Creton(3), Matthew J. Fuchter(3), Gary Newton(3), Robert Yan(3), Michael Schneider(3), Matthias Festag(3), Laura Andrews(3), Lorrene A. Buckley(3), Susan Sparrow(3), Samuel J. Jackson(2), Michael E. Grant(2)