Charles C. King

University of California, San Diego — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

29h-index4.1kcitations89works0.02yr avg
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Research Topics

Protein Kinase Regulation and GTPase Signaling(16), Pluripotent Stem Cells Research(13), Pancreatic function and diabetes(11), Ubiquitin and proteasome pathways(10), CRISPR and Genetic Engineering(7)

Publications88 total

A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction
Nature Structural & Molecular Biology·2022· 59 citedOpen Access
194: PROCALCITONIN KINETICS MAY INDICATE PRESENCE OF SECONDARY BACTERIAL INFECTIONS IN COVID-19 ARDS
Critical Care Medicine·2021
Procalcitonin Increase Is Associated with the Development of Critical Care-Acquired Infections in COVID-19 ARDS
Antibiotics·2021· 27 citedOpen Access
Differences in Inflammatory Marker Kinetics between the First and Second Wave of COVID-19 Patients Admitted to the ICU: A Retrospective, Single-Center Study
Journal of Clinical Medicine·2021· 8 citedOpen Access
A PKA Inhibitor Motif within Smoothened Controls Hedgehog Signal Transduction
2021· 2 cited
mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif
Science Signaling·2021· 108 citedOpen Access
The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch
Molecular and Cellular Biology·2021· 7 citedOpen Access
548: ICU Risk Prediction From Commonly Measured Clinical Data Using Artificial Neural Network Tools
Critical Care Medicine·2020· 1 cited
Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study
The Lancet Respiratory Medicine·2020· 257 citedOpen Access
CDK1‐dependent Phosphorylation of the Tumor Suppressor Phosphatase, PHLPP1, Regulates the Mitotic PHLPP1 Interactome
The FASEB Journal·2020
PTPN22 phosphorylation acts as a molecular rheostat for the inhibition of TCR signaling
Science Signaling·2020· 22 citedOpen Access
CDK1‐dependent Phosphorylation of the Tumor Suppressor Phosphatase, PHLPP1, Regulates the Mitotic PHLPP1 Interactome
The FASEB Journal·2018
mTOR activity in AIDS-related diffuse large B-cell lymphoma
PLoS ONE·2017· 5 citedOpen Access
The non-coding landscape of head and neck squamous cell carcinoma
Oncotarget·2016· 60 citedOpen Access
Brief review: cell replacement therapies to treat type 1 diabetes mellitus
Clinical Diabetes and Endocrinology·2016· 8 citedOpen Access
Endogenous RIIβ is constitutionally phosphorylated in 3T3 and HeLa cells.
Figshare·2015Open Access
Protein kinase Cζ exhibits constitutive phosphorylation and phosphatidylinositol-3,4,5-triphosphate-independent regulation
Biochemical Journal·2015· 39 cited
Crystal structures of the RIIβ holoenzyme showing active site phosphorylation in the presence of calcium.
Figshare·2015Open Access
Single turnover and pre-steady-state kinetics for RIIβ holoenzyme phosphorylation in the presence of Mg<sup>2+</sup> versus Ca<sup>2+</sup>.
Figshare·2015Open Access
Helicobacter pylori modulates host cell survival regulation through the serine-threonine kinase, 3-phosphoinositide dependent kinase 1 (PDK-1)
BMC Microbiology·2015· 14 citedOpen Access
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Frequent Co-authors

Andrew Hinton(8), Gary Bokoch(8), Alberto Hayek(7), Alexandra C. Newton(7), Ana D. Lopez(6), Susan S. Taylor(6), Frank T. Zenke(4), Edwin L. Thomas(4), M. Margaret Jefferson(4), Gillian M. Beattie(3), Charlotte Killick(3), Owen Richards(3), Yusuf Cheema(3), Tamás Szakmány(3), Benjamin P. Bohl(3), Mira Sastri(3), Gary B. Fogel(3), Nathan Bucay(2), Meri T. Firpo(2), Catherine Bailey(2)