Gerald L. Messerschmidt

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index750citations32works0.02yr avg
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Research Topics

Cancer Research and Treatments(5), Virus-based gene therapy research(4), Cancer Immunotherapy and Biomarkers(3), Immunotherapy and Immune Responses(3), CAR-T cell therapy research(3)

Publications32 total

Key issues in the development and approval of new anti-cancer immune therapies.
Journal of Clinical Oncology·2020
A precision medicine tool “Knowledge Frames” to explain poor results of STING agonist trials.
Journal of Clinical Oncology·2020
Efficiency: Minimizing dose escalation steps by calculating human dosing preclinically.
Journal of Clinical Oncology·2020· 1 cited
Abstract 543: Dinutuximab binds specifically to disialoganglioside-2
Cancer Research·2019· 3 cited
Abstract 543: Dinutuximab binds specifically to disialoganglioside-2
Clinical Research (Excluding Clinical Trials)·2019· 1 cited
Cancer Clonal Theory, Immune Escape, and Their Evolving Roles in Cancer Multi-Agent Therapeutics
Current Oncology Reports·2017· 12 cited
How Cancers Escape Immune Destruction and Mechanisms of Action for the New Significantly Active Immune Therapies: Helping Nonimmunologists Decipher Recent Advances
The Oncologist·2016· 93 citedOpen Access
Extended evaluation of a phase 1/2 trial on dosing, safety, immunogenicity, and overall survival after immunizations with an advanced-generation Ad5 [E1-, E2b-]-CEA(6D) vaccine in late-stage colorectal cancer
Cancer Immunology Immunotherapy·2015· 53 citedOpen Access
Vincristine sulfate liposomes injection (VSLI) “bridging” to potentially curative hematopoietic stem cell transplantation (HSCT) in adults with Philadelphia chromosome negative (Ph-) acute lymphoblastic leukemia (ALL).
Journal of Clinical Oncology·2011· 3 cited
Holter monitor cardiac safety evaluation of vincristine sulfate liposomes injection (VSLI) administered to humans with active cancer.
Journal of Clinical Oncology·2011
Marqibo® (vincristine sulfate liposomes injection; VSLI) In the Treatment of Adult Patients with Advanced, Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL): A Combined Analysis of the VSLI-06 and RALLY Studies
Blood·2010· 5 cited
283 POSTER Phase 1 trial of SNS-314, a novel selective inhibitor of Aurora kinases A, B, and C, in advanced solid tumor patients
European Journal of Cancer Supplements·2008· 8 cited
In Regard to Münter et al. Changes in Salivary Gland Function After Radiotherapy of Head and Neck Tumors Measured by Quantitative Pertechnetate Scintigraphy: Comparison of Intensity-Modulated Radiotherapy and Conventional Radiation Therapy With and Without Amifostine. (Int J Radiat Oncol Biol Phys 2007;67:651–659)
International Journal of Radiation Oncology*Biology*Physics·2007
Carmustine, Ara C, cyclophosphamide and etoposide with autologous bone marrow transplantation in relapsed or refractory lymphoma: a dose-finding study.
PubMed·1994· 7 cited
Treatment of cancer chemotherapy-associated thrombotic thrombocytopenic purpura/hemolytic uremic syndrome by protein A immunoadsorption of plasma
Cancer·1993· 107 citedOpen Access
[Follow-up of chronic hepatitis B in patients with kidney transplantation: comparison between kidney transplant patients and hemodialysis patients].
PubMed·1992
Use of protein A immunoadsorption as a treatment for thrombocytopenia in HIV-infected homosexual men
AIDS·1991· 18 cited
Minimal toxicity during protein a immunoadsorption treatment of malignant disease: An outpatient therapy
Journal of Clinical Apheresis·1991· 23 cited
A prospective randomized trial of HLA-matched versus mismatched single-donor platelet transfusions in cancer patients
Cancer·1988· 27 citedOpen Access
Acute neurologic dysfunction after high-dose etoposide therapy for malignant glioma
Cancer·1988· 48 citedOpen Access
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Frequent Co-authors

Harry W. Snyder(4), Juergen H. Bertram(4), Joseph P. Balint(4), Frank R. Jones(4), David H. Henry(4), A B Deisseroth(4), Robert C. Young(3), William Perkins(3), Richard Leff(3), David B. Johnson(3), C Bowles(3), Steven R. Deitcher(3), Steve Gyorffy(3), Al Blunt(3), Robert F. Ozols(2), Albert Deisseroth(2), Nasser Javadpour(2), Audrey Barlock(2), A Mittelman(2), Sharon K. Cochran(2)