T. Nozaki

The University of Tokyo — Japan

Medicine · Health Sciences

7h-index528citations19works2.02yr avg
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Research Topics

Amoebic Infections and Treatments(6), PARP inhibition in cancer therapy(5), Cancer Research and Treatments(5), DNA Repair Mechanisms(4), Trypanosoma species research and implications(3)

Publications19 total

A New Multiplex PCR Assay Reveals the Occurrence of E. bangladeshi alongside E. histolytica and E. moshkovskii in Eastern India
Acta Parasitologica·2024· 2 cited
Crystal structure of Trypanosoma brucei gambiense glycerol kinase complex with AMP-PNP.
2019
Crystal structure of Trypanosoma brucei gambiense glycerol kinase phosphorylated at Thr12(pyrophosphatase reaction)
2019
Crystal structure of Trypanosoma brucei glycosomal isocitrate dehydrogenase in complex with NADP+, alpha-ketoglutarate and ca2+
2018
Reaction intermediate structure of Entamoeba histolytica methionine gamma-lyase 1 containing Michaelis complex and methionine imine-pyridoxamine-5'-phosphate
2010· 1 cited
Reaction intermediate structure of Entamoeba histolytica methionine gamma-lyase 1 containing methionine imine-pyridoxamine-5'-phosphate and alpha-amino-alpha, beta-butenoic acid-pyridoxal-5'-phosphate
2010
Reaction intermediate structure of Entamoeba histolytica methionine gamma-lyase 1 containing Michaelis complex and alpha-amino-alpha, beta-butenoic acid-pyridoxal-5'-phosphate
2010
Reaction intermediate structure of Entamoeba histolytica methionine gamma-lyase 1 tetramer containing Michaelis complex and methionine-pyridoxal-5'-phosphate
2010
Poly(ADP-ribose) Glycohydrolase Deficiency Sensitizes Mouse ES Cells to DNA Damaging Agents
Current Cancer Drug Targets·2009· 35 cited
X-ray crystal structure analyses of methionine γ-lyase 1 and 2 from<i>Entamoeba histolytica</i>
Acta Crystallographica Section A Foundations of Crystallography·2008Open Access
Improvement of the Spi<sup>‐</sup> assay for mutations in <i>gpt</i> delta mice by including magnesium ions during plaque formation
Environmental and Molecular Mutagenesis·2003· 8 cited
Improvement of the Spi assay for gpt delta mice by including magnesium ions during plaque formation
Taikai Program Yoshisyu of the Environmental Mutagen Society of Japan·2002
Trophoblast functions, angiogenesis and remodeling of the maternal vasculature in the placenta
Molecular and Cellular Endocrinology·2002· 279 cited
Isolation and Cloning of Rat Poly(ADP-Ribose) Glycohydrolase: Presence of a Potential Nuclear Export Signal Conserved in Mammalian Orthologs
The Journal of Biochemistry·1999· 47 cited
The human poly(ADP-ribose) glycohydrolase maps to chromosome 10q11.23-21.1 by fluorescence in situ hybridization.
PubMed·1998· 6 cited
Analysis of cysteine biosynthetic pathway in entamoeba histolytica: involvement of cysteine in the antioxidative mechanism
Parasitology International·1998
Role of poly(ADP-ribose) polymerase in cell-cycle checkpoint mechanisms following γ-irradiation
Biochimie·1995· 63 cited
Inducible binding of human lymphocytes to hyaluronate via CD44 does not require cytoskeleton association but does require new protein synthesis.
The Journal of Immunology·1994· 64 citedOpen Access
Noncovalent Interaction between Poly(ADP-Ribose) and Cellular Proteins: An Application of a Poly(ADP-Ribose) Western Blotting Method to Detect Poly(ADP-Ribose) Binding on Protein-Blotted Filter
Biochemical and Biophysical Research Communications·1994· 23 cited

Frequent Co-authors

Mitsuko Masutani(8), S. Harada(7), T. Karaki(5), Akira Shimizu(5), Hitoshi Nakagama(4), D. Sato(4), Takashi Sügimura(3), Hisako Fujihara(3), Nobuo Kamada(3), T. Sugimura(3), E.O. Balogun(3), D.K. Inaoka(3), Yoshinori Watanabe(3), Kiyoshi Kita(3), T. Shiba(3), Takashi Shimokawa(2), Yoshiro Aoki(2), Atsushi Shibata(2), Kenichi Masumura(2), S Kobayashi(2)