Allen D. Roses

Duke University — United States

Medicine · Health Sciences

93h-index55.7kcitations494works0.02yr avg
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Research Topics

Alzheimer's disease research and treatments(161), Genetic Neurodegenerative Diseases(56), Bioinformatics and Genomic Networks(50), Dementia and Cognitive Impairment Research(47), Mitochondrial Function and Pathology(37)

Publications490 total

Disease-modifying effects of an <i>SCAF4</i> structural variant in a predominantly <i>SOD1</i> ALS cohort
Neurology Genetics·2020· 9 citedOpen Access
Myasthenia Gravis
2019
The Metabolism Of Apolipoprotein E And The Alzheimer’s Diseases *
2019
Corrigendum to “The Biological Foundation of the Genetic Association of TOMM40 with Late-onset Alzheimer's disease” [Biochim. Biophys. Acta 1863/11 (2017) 2973–2986]
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2018
Characterization of <i>APOE</i> and <i>TOMM40</i> allele frequencies in the Japanese population
Alzheimer s & Dementia Translational Research & Clinical Interventions·2017· 13 citedOpen Access
The biological foundation of the genetic association of TOMM40 with late-onset Alzheimer's disease
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2017· 54 citedOpen Access
APOE ε4-TOMM40 ‘523 haplotypes and the risk of Alzheimer’s disease in older Caucasian and African Americans
PLoS ONE·2017· 58 citedOpen Access
[P4–432]: CONSEQUENCES OF INCREASED TOMM40 EXPRESSION ON CELLULAR ENERGETICS
Alzheimer s & Dementia·2017Open Access
[IC‐P‐066]: AD FAMILY HISTORY MODULATES EFFECTS OF TOMM40 ‘523’ POLY‐T ON MTL ATROPHY AND HYPOMETABOLISM IN PRECLINICAL AND AD COHORTS
Alzheimer s & Dementia·2017Open Access
Family history and <i>TOMM40</i> '523 interactive associations with memory in middle‐aged and Alzheimer's disease cohorts
Alzheimer s & Dementia·2017· 12 citedOpen Access
Editorial overview: Molecular &amp; genetic basis of disease
Current Opinion in Genetics & Development·2017
The <i>Alu</i> neurodegeneration hypothesis: A primate‐specific mechanism for neuronal transcription noise, mitochondrial dysfunction, and manifestation of neurodegenerative disease
Alzheimer s & Dementia·2017· 69 citedOpen Access
<i>TOMM40</i> ′523 variant and cognitive decline in older persons with <i>APOE</i> ε3/3 genotype
Neurology·2017· 70 citedOpen Access
The effects of PPARγ on the regulation of the TOMM40 - APOE - C1 genes cluster
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2017· 30 citedOpen Access
P4‐293: <i>APOE–TOMM40</i> ‘523 Haplotypes and the Risk of Alzheimer’S Disease in Older Caucasian and African Americans
Alzheimer s & Dementia·2016
P4‐383: Characterization of the Screened Population for the Tommorrow Study: a Pharmacogenetics‐Supported Clinical Trial to Delay the Onset of Mild Cognitive Impairment Due to Alzheimer’S Disease
Alzheimer s & Dementia·2016
P4‐301: TOMM40 Overexpression and PPAR‐GAMMA Agonists Protect Cells From Pathophysiological Stress Associated with Late Onset Alzheimer's Disease
Alzheimer s & Dementia·2016· 1 cited
P2‐075: Alzheimer's Disease Family History Modulates Effects of '523 TOMM40 on Memory Decline and Medial Temporal Pathology
Alzheimer s & Dementia·2016Open Access
P4‐395: Clinical Trials in the Preclinical to MCI Stages of AD: Cross‐Cultural Validation and Normative Study of the Tommorrow Neuropsychological Battery
Alzheimer s & Dementia·2016
P4‐295: <i>TOMM40</i> ‘523 Variant and Cognitive Decline in Community Based Older Persons with <i>APOE</i> E3/3 GENOTYPE
Alzheimer s & Dementia·2016Open Access
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Frequent Co-authors

Ann M. Saunders(20), Jeffery M. Vance(13), Warren J. Strittmatter(11), Margaret A. Pericak‐Vance(10), D. E. Schmechel(8), Jonathan L. Haines(7), Lefkos Middleton(6), John R. Gilbert(5), Donald E. Schmechel(5), P. C. Gaskell(4), Gary W. Small(4), Peter St George‐Hyslop(4), James F. Gusella(4), Dmitry Goldgaber(4), Karl H. Weisgraber(4), Eric Lai(4), Elizabeth H. Corder(3), Christine Hulette(3), Barbara J. Crain(3), Teepu Siddique(3)