Joerg Czech

Sanofi (Germany) — Germany

Medicine · Health Sciences

8h-index445citations9works0.02yr avg
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Research Topics

Blood Coagulation and Thrombosis Mechanisms(3), Sirtuins and Resveratrol in Medicine(3), Biochemical and Molecular Research(3), Click Chemistry and Applications(2), PARP inhibition in cancer therapy(2)

Publications9 total

Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders
Scientific Reports·2022· 24 citedOpen Access
A Solid Supported Membrane-Based Technology for Electrophysical Screening of B0AT1-Modulating Compounds
SLAS DISCOVERY·2021· 11 cited
Novel Inhibitors of Nicotinamide-N-Methyltransferase for the Treatment of Metabolic Disorders
Molecules·2021· 20 citedOpen Access
Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase
Bioorganic & Medicinal Chemistry Letters·2018· 36 citedOpen Access
Structure-based design of amidinophenylurea-derivatives for factor VIIa inhibition
Bioorganic & Medicinal Chemistry Letters·2004· 20 citedOpen Access
Design, Synthesis, and Structure—Activity Relationship of a New Class of Amidinophenylurea‐Based Factor VIIa Inhibitors.
ChemInform·2003
Design, synthesis, and structure–activity relationship of a new class of amidinophenylurea-based factor VIIa inhibitors
Bioorganic & Medicinal Chemistry Letters·2003· 28 citedOpen Access
Prodrugs of Anthracyclines for Use in Antibody-Directed Enzyme Prodrug Therapy
Journal of Medicinal Chemistry·1998· 80 cited
Elucidation of the mechanism enabling tumor selective prodrug monotherapy.
PubMed·1998· 226 cited

Frequent Co-authors

Herman Schreuder(6), Sven Ruf(4), Mahanandeesha S. Hallur(3), Indu N. Swamy(3), Rajendra Kristam(3), Aimo Kannt(3), Saravanakumar Dhakshinamoorthy(3), Sridharan Rajagopal(3), Otmar Klingler(3), Hans Matter(3), Manfred Schudok(3), M. Lorenz(3), H. Peter Nestler(3), Klaus Bosslet(2), Rainer H. Straub(2), Manfred Gerken(2), Jean‐Pierre Gesson(2), Michel Koch(2), Claude Monneret(2), V. P. Rama Kishore Putta(2)