Hirokazu Shigematsu

University of Shizuoka — Japan

Medicine · Health Sciences

25h-index5.5kcitations46works0.02yr avg
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Research Topics

Acute Myeloid Leukemia Research(18), Immune cells in cancer(7), Epigenetics and DNA Methylation(5), Hematopoietic Stem Cell Transplantation(5), Immune Cell Function and Interaction(5)

Publications46 total

Liposomal Amiodarone Augments Anti-arrhythmic Effects and Reduces Hemodynamic Adverse Effects in an Ischemia/Reperfusion Rat Model
Cardiovascular Drugs and Therapy·2013· 46 cited
Development of anti-HB-EGF immunoliposomes for the treatment of breast cancer
Journal of Controlled Release·2011· 55 cited
The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model
Journal of Clinical Investigation·2009· 110 citedOpen Access
Notch1 Expression Is Regulated at Post-Transcriptional Level by 3′UTR Region in Hematopoietic Stem Cell Development
Blood·2008
OTT-MAL Activates the Notch Signaling Transcription Factor RBPJ and Cooperates with Mutant MPL to Induce Acute Megakaryoblastic Leukemia
Blood·2008
Bone marrow or foetal liver cells fail to induce islet regeneration in diabetic Akita mice
Diabetes/Metabolism Research and Reviews·2008· 11 citedOpen Access
Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage
The Journal of Experimental Medicine·2008· 77 citedOpen Access
Reciprocal Activation of GATA-1 and PU.1 Marks Initial Specification of Hematopoietic Stem Cells into Myelo-Erythroid and Myelo-Lymphoid Lineages.
Blood·2007· 3 cited
In Vivo Permanent Marking of Cells with RAG1 Activation History Demonstrates That Lymphoid and Myeloid Derived Dendritic Cells Operate an Identical Developmental Program after Their Lineage Commitment.
Blood·2007
Reciprocal Activation of GATA-1 and PU.1 Marks Initial Specification of Hematopoietic Stem Cells into Myeloerythroid and Myelolymphoid Lineages
Cell stem cell·2007· 297 citedOpen Access
Regulation of B Versus T Lymphoid Lineage Fate Decision by the Proto-Oncogene LRF
Science·2007· 207 citedOpen Access
<i>Ott1</i> ( <i>Rbm15</i> ) has pleiotropic roles in hematopoietic development
Proceedings of the National Academy of Sciences·2007· 92 citedOpen Access
Delineation of the Common Developmental Pathway for Granulocyte/Monocyte and Lymphoid Lineages by Using an Expression Reporter for PU.1.
Blood·2006· 1 cited
LRF/Pokemon Plays a Pivotal Role in B Versus T Lymphoid Lineage Fate Decision at the Early Lymphoid Progenitor Stage by Opposing Notch1 Signaling.
Blood·2006
Ott1(Rbm15) Is Essential for Pre-B Differentiation and Has an Inhibitory Role in Myeloid and Megakaryocytic Lineages.
Blood·2006
In Vivo Permanent Marking of Cells with RAG1 Activation History Demonstrates Only a Minor Contribution of the Lymphoid Pathway to Dendritic Cell Development.
Blood·2006
Notch1 Expression Is Regulated at Translational Level by 3′UTR Region in Hematopoietic Stem Cell Development.
Blood·2006
The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages
Genes & Development·2006· 286 citedOpen Access
Essential Role for Cyclin D3 in Granulocyte Colony-Stimulating Factor-Driven Expansion of Neutrophil Granulocytes
Molecular and Cellular Biology·2006· 44 citedOpen Access
Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis
Proceedings of the National Academy of Sciences·2005· 339 citedOpen Access
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Frequent Co-authors

Koichi Akashi(35), Hiromi Iwasaki(21), Yojiro Arinobu(16), Shinichi Mizuno(11), Ifor R. Williams(10), D. Gary Gilliland(9), Tadafumi Iino(8), Hidetoshi Ozawa(7), Yong Chong(7), Yoshiyuki Niho(7), Daniel G. Tenen(6), Shin-ichi Mizuno(6), Teruhisa Otsuka(6), Benjamin H. Lee(5), Fumitou Arima(5), Jeffery L. Kutok(4), Susan Chan(4), Philippe Kastner(4), Michael F. Gurish(4), Thomas Mercher(4)