Wendy W. Pang

Medicine · Health Sciences

16h-index7.4kcitations73works0.92yr avg
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Research Topics

Acute Myeloid Leukemia Research(25), Hematopoietic Stem Cell Transplantation(23), Immune Cell Function and Interaction(11), Erythrocyte Function and Pathophysiology(9), Mast cells and histamine(8)

Publications73 total

Initial Results From A Phase 2, Open-label Extension Study To Evaluate The Long-term Safety And Efficacy Of The Anti-KIT Briquilimab Antibody In Adults With Chronic Urticaria
Journal of Allergy and Clinical Immunology·2026
Results from SPOTLIGHT, a Phase 1b/2a Dose Escalation Study of the anti-c-Kit Briquilimab Antibody in Adults with Inducible Urticaria (CIndU) Who Remain Symptomatic Despite H-1 Antihistamine Treatment
Journal of Allergy and Clinical Immunology·2026
Hematopoietic stem cell transplantation using briquilimab (Anti-CD117 Antibody-Conditioning), immunosuppression and TCRαβ+ T-cell/CD19+ B-cell depleted haploidentical grafts in patients with fanconi anemia: An approach without irradiation, busulfan and calcineurin inhibitors.
Blood·2025· 1 citedOpen Access
Human <scp>KIT</scp> Antibody Briquilimab Diminishes Anaphylactic Responses in Mice Expressing Chimeric Human‐Mouse <scp>KIT</scp>
Allergy·2025Open Access
Anti-KIT antibody, briquilimab, induces mast cell apoptosis and depletion in nonhuman primates
Journal of Allergy and Clinical Immunology·2025· 2 cited
Irradiation- and busulfan-free stem cell transplantation in Fanconi anemia using an anti-CD117 antibody: a phase 1b trial
Nature Medicine·2025· 5 citedOpen Access
Briquilimab, an Anti-c-Kit Antibody, Induces Durable Depletion of Mast Cells (MCs) Across Multiple Tissues in Mice Expressing Chimeric Human/Mouse CD117 (c-Kit)
Journal of Allergy and Clinical Immunology·2025Open Access
Initial results from BEACON, a phase 1b/2a dose escalation study of the anti-c-Kit briquilimab antibody in adults with chronic spontaneous urticaria (CSU)
Journal of Allergy and Clinical Immunology·2025· 3 cited
Briquilimab Potently Inhibits Stem Cell Factor (SCF)/c-Kit Signaling and Induces Mast Cell Apoptosis
Journal of Allergy and Clinical Immunology·2025· 1 citedOpen Access
Briquilimab, an Anti-Human CD117 Antibody, Prevents Epicutaneous Oxazolone-Induced Features of Dermatitis in Mouse Model Expressing Chimeric Human/Mouse CD117
Journal of Allergy and Clinical Immunology·2025
Briquilimab, an Anti-Human CD117 Antibody, Treats Low-Calcemic Vitamin D3 Analog MC903-Induced Dermatitis in Mouse Model Expressing Chimeric Human/Mouse CD117
Journal of Allergy and Clinical Immunology·2025Open Access
REMOVED: Allogeneic Hematopoietic Cell Transplantation with Briquilimab (JSP191) Anti-CD117 Antibody-Based Nonmyeloablative Conditioning for GATA2 Deficiency
Transplantation and Cellular Therapy·2025
Adding CD117 Antibody to Alemtuzumab, Low Dose Total Body Irradiation (TBI), and Sirolimus for Matched Related Donor (MRD) Hematopoietic Cell Transplant (HCT) in Sickle Cell Disease (SCD): Initial Results
Blood·2024· 1 cited
BRIQUILIMAB POTENTLY INHIBITS STEM CELL FACTOR (SCF)/C-KIT SIGNALING, AND MAST CELL (MC) DEGRANULATION AND SURVIVAL
Annals of Allergy Asthma & Immunology·2024
BRIQUILIMAB POTENTLY BLOCKS STEM CELL FACTOR (SCF)/C-KIT SIGNALING IN PRIMARY HUMAN MAST CELLS
Annals of Allergy Asthma & Immunology·2024
Pharmacokinetics of Briquilimab as a Conditioning Agent for Hematopoietic Stem Cell Transplantation in Patients With Severe Combined Immunodeficiency, Myelodysplastic Syndrome, or Acute Myeloid Leukemia
Transplantation and Cellular Therapy·2024· 1 cited
Amelioration Of Mrgprb2-Mediated Anaphylactoid Drug Reactions With Briquilimab, An Anti-CD117 Antibody, Through Mast Cell Depletion In Mice Expressing Chimeric Human And Mouse CD117
Journal of Allergy and Clinical Immunology·2024· 1 citedOpen Access
Briquilimab, An Anti-CD117 Antibody, Prevents Cockroach Allergen Induced Allergic Asthma In Mice Expressing Chimeric Human And Mouse CD117
Journal of Allergy and Clinical Immunology·2024· 1 citedOpen Access
Briquilimab, An Anti-CD117 Antibody, Prevents Passive Systemic Anaphylaxis In Mice Expressing Chimeric Human And Mouse CD117 Through Mast Cell Depletion
Journal of Allergy and Clinical Immunology·2024· 1 citedOpen Access
Radiation and Busulfan-Free Hematopoietic Stem Cell Transplantation Using Briquilimab (JSP191) Anti-CD117 Antibody-Conditioning, Transient Immunosuppression and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts in Patients with Fanconi Anemia
Blood·2023· 8 cited
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Frequent Co-authors

Irving L. Weissman(25), Judith A. Shizuru(14), Hye‐Sook Kwon(11), Agnieszka Czechowicz(9), Christopher Y. Park(8), Stanley L. Schrier(8), Ravindra Majeti(6), Mark P. Chao(6), Elizabeth Price(6), Janel Long-Boyle(6), Robertson Parkman(5), Revati Nerkar(5), Siddhartha Jaiswal(4), John V. Pluvinage(4), Amelia Scheck(4), Yan Yi Chan(4), Aaron C. Logan(4), Rajni Agarwal(4), Lori Muffly(4), Andrew Artz(4)