Philip W. Majerus

Biochemistry, Genetics and Molecular Biology · Life Sciences

96h-index31.5kcitations265works0.02yr avg
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Research Topics

Protein Kinase Regulation and GTPase Signaling(45), Cellular transport and secretion(44), Blood Coagulation and Thrombosis Mechanisms(39), Pancreatic function and diabetes(29), Phytase and its Applications(22)

Publications264 total

INO-4995 Therapeutic Efficacy Is Enhanced with Repeat Dosing in Cystic Fibrosis Knockout Mice and Human Epithelia
UNC Libraries·2020Open Access
I. IDENTIFICATION OF THE ENZYMES OF GLUTATHIONE SYNTHESIS IN HEMOLYSATES
2017
Isolation of 1-monomethylphosphoinositol 4,5-bisphosphate (a product of methanolysis of inositol 1,2-(cyclic)-4,5-trisphosphate) from Swiss mouse 3T3 cells (inositol cyclic phosphates/signal transduction/inositol cyclic trisphosphate)
2016
Human coagulation factor Va is a c protein C (blood clotting/factor V/clotting inhibitors)
2016
An aspirin a day
Advances in Biological Regulation·2013· 3 cited
Myotubularin-related protein (MTMR) 9 determines the enzymatic activity, substrate specificity, and role in autophagy of MTMR8
Proceedings of the National Academy of Sciences·2012· 61 citedOpen Access
Regulation of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) by reversible lysine acetylation
Proceedings of the National Academy of Sciences·2012· 16 citedOpen Access
The role of myotubularin-related phosphatases in the control of autophagy and programmed cell death
Advances in Biological Regulation·2011· 21 cited
Inositol Polyphosphate 4-Phosphatase B as a Regulator of Bone Mass in Mice and Humans
Cell Metabolism·2011· 61 citedOpen Access
Wandering through the laboratory.
Journal of Biological Chemistry·2011Open Access
Wandering through the Laboratory
Journal of Biological Chemistry·2010· 1 citedOpen Access
Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers
Proceedings of the National Academy of Sciences·2010· 288 citedOpen Access
The role of inositol polyphosphate 4-phosphatase 1 in platelet function using a weeble mouse model
Advances in Enzyme Regulation·2010· 6 cited
Expression of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) and its role in neural tube defects
Advances in Enzyme Regulation·2009· 19 citedOpen Access
Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies
Nature Genetics·2009· 408 citedOpen Access
Neural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinase
Proceedings of the National Academy of Sciences·2009· 55 citedOpen Access
Isolation of Vitamin B12-binding Proteins Using Affinity Chromatography Preparation And Properties Of Vitamin B12-Sepharose
Nutrition Reviews·2009· 2 cited
INO-4995 Therapeutic Efficacy Is Enhanced with Repeat Dosing in Cystic Fibrosis Knockout Mice and Human Epithelia
American Journal of Respiratory Cell and Molecular Biology·2009· 11 citedOpen Access
Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4‐phosphatase‐1
EMBO Reports·2009· 76 citedOpen Access
MTMR9 Increases MTMR6 Enzyme Activity, Stability, and Role in Apoptosis
Journal of Biological Chemistry·2008· 56 citedOpen Access
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Frequent Co-authors

N Stanford(6), Thomas Connolly(6), David B. Wilson(6), Nancy Lewis Baenziger(6), T E Bross(5), Anne B. Jefferson(4), G J Roth(3), Theodora S. Ross(3), Hidemi Ishii(3), Vinay S. Bansal(3), Frank A. Norris(3), Joseph P. Miletich(3), Marina V. Kisseleva(3), Randy L. Bell(2), John W. Burch(2), Monita P. Wilson(2), Craig M. Jackson(2), Ikuro Maruyama(2), G. N. Brodie(2), S M Prescott(2)