Lifei Nie

Chinese Academy of Sciences — China

Chemistry · Physical Sciences

12h-index273citations32works4.12yr avg
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Research Topics

Synthesis and biological activity(14), Quinazolinone synthesis and applications(11), Cancer therapeutics and mechanisms(6), Synthesis and Biological Evaluation(6), Synthesis and Characterization of Heterocyclic Compounds(4)

Publications32 total

Design and synthesis of novel indolinone Aurora B kinase inhibitors based on fragment-based drug discovery (FBDD)
Molecular Diversity·2025
Aurone and its analogues as targeted drugs for the anticancer treatment
Bioorganic & Medicinal Chemistry·2025
Scaffold-Hopping Design and Synthesis of Thieno[3,2-d]pyrimidines: Anticancer Activity, Apoptosis Induction, and In Silico Inhibition of CDKs
International Journal of Molecular Sciences·2025Open Access
Design and Synthesis of Novel Indolinone Aurora B Kinase Inhibitors Based on Fragment-Based Drug Discovery (FBDD)
2025Open Access
Pyrrolopyrimidines: Design, Synthesis and Antitumor Properties of Novel Tricyclic Pyrrolo [2,3-d]pyrimidine Derivatives
Molecules·2025· 1 citedOpen Access
Synthesis of Novel 7-Phenyl-2,3-Dihydropyrrolo[2,1-b]Quinazolin-9(1H)-ones as Cholinesterase Inhibitors Targeting Alzheimer’s Disease Through Suzuki–Miyaura Cross-Coupling Reaction
Molecules·2025· 6 citedOpen Access
Imidazole Hybrids: A Privileged Class of Heterocycles in Medicinal Chemistry with New Insights into Anticancer Activity
Molecules·2025· 18 citedOpen Access
Modular Construction of Chiral Aminopiperidine via Palladium-Catalyzed Hydroamination of 1,2-Dihydropyridine
Organic Letters·2025· 2 cited
Design, Synthesis, In Vitro Evaluation of New Tetrahydrooxazolo [5′,4′:4,5]Pyrimido[1,2‐<i>a</i>]Azepinone Derivatives as Anticancer Agents
Journal of Heterocyclic Chemistry·2024
Design, synthesis, biological evaluation of a new tricyclicthiazolopy‐rimidinone derivatives as acetylcholinesterase inhibitors
Journal of Heterocyclic Chemistry·2024· 5 citedOpen Access
Synthesis of tricyclic pyrazolopyrimidine arylidene ester derivatives and their cytotoxic and molecular docking evaluations
Journal of Heterocyclic Chemistry·2024· 13 cited
Discovery of novel (E)-1-methyl-9-(3-methylbenzylidene)-6,7,8,9-tetrahydropyrazolo[3,4-d]pyrido[1,2-a]pyrimidin-4(1H)-one as DDR2 kinase inhibitor: Synthesis, molecular docking, and anticancer properties
Bioorganic Chemistry·2023· 15 cited
Front Cover: Furo[2,3‐<i>d</i>]pyrimidines as Mackinazolinone/Isaindigotone Analogs: Synthesis, Modification, Antitumor Activity, and Molecular Docking Study (Chem. Biodiversity 3/2023)
Chemistry & Biodiversity·2023· 1 citedOpen Access
Furo[2,3‐<i>d</i>]pyrimidines as Mackinazolinone/Isaindigotone Analogs: Synthesis, Modification, Antitumor Activity, and Molecular Docking Study
Chemistry & Biodiversity·2023· 13 cited
Synthesis of Diethyl 2,5-Diaminothiophene-3,4-dicarboxylate Derivatives and Antitumor Activity Study
Chinese Journal of Organic Chemistry·2023· 1 citedOpen Access
Parallel synthesis of condensed pyrimidine-thiones and their antitumor activities
Research on Chemical Intermediates·2022· 17 cited
Novel pyrazolo[3,4-d]pyrimidines as potential anticancer agents: Synthesis, VEGFR-2 inhibition, and mechanisms of action
Biomedicine & Pharmacotherapy·2022· 34 citedOpen Access
Parallel synthesis of condensed pyrimidine-thiones and their antitumor activities
Research Square (Research Square)·2022Open Access
Design, combinatorial synthesis and cytotoxic activity of 2-substituted furo[2,3-d]pyrimidinone and pyrrolo[2,3-d]pyrimidinone library
Molecular Diversity·2022· 21 cited
Design, synthesis, in vitro evaluation of a new pyrrolo[1,2‐<i>a</i>]thiazolo[5,4‐<i>d</i>]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease
Journal of Heterocyclic Chemistry·2022· 18 cited
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Frequent Co-authors

Haji Akber Aisa(27), Khurshed Bozorov(21), Jiangyu Zhao(15), Chao Niu(10), Rustamkhon Kuryazov(9), Buer Song(7), Yan Zeng(7), Zukela Ruzi(6), Zarifa Murtazaeva(4), Jianping Yong(4), Jiangyu Zhao(4), Jiangyu Zhao(4), Azizbek Nasrullaev(3), Danling Tang(3), Miaomiao Shi(3), Liu Liu(2), Anvarjon Buronov(2), Shukhrat Gaybullaev(2), Davron Turgunov(2), Xueling Hou(2)