Kaoru Shimada

Brigham and Women's Hospital — United States

Medicine · Health Sciences

33h-index14.2kcitations207works0.82yr avg
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Research Topics

Antibiotics Pharmacokinetics and Efficacy(38), Pneumonia and Respiratory Infections(33), HIV Research and Treatment(24), HIV/AIDS drug development and treatment(21), Antibiotic Resistance in Bacteria(18)

Publications206 total

1270 APOE tumor-associated macrophages and CD4-DOCK4 T cells reveal distinct microenvironmental features in HER2-Low and HER2–0 hormone receptor-positive breast cancer
Regular and Young Investigator Award Abstracts·2025Open Access
Multicenter prospective EN-MARK study: efficacy of third-line trastuzumab deruxtecan and dynamic changes in biomarkers, including HER2 status
ESMO Gastrointestinal Oncology·2025· 1 citedOpen Access
APOE+ Tumor-Associated Macrophages and CD4-DOCK4 T Cells Reveal Distinct Microenvironmental Features in HER2-Low and HER2-0 Hormone Receptor-Positive Breast Cancer
2025Open Access
Abstract P5-08-11: Comprehensive characterization of the immune landscape in HER2-low and HER2-0 hormone receptor positive tumors
Clinical Cancer Research·2025
Abstract 1172: An estrogen receptor signaling transcriptional program linked to immune evasion in human hormone receptor-positive breast cancer
Cancer Research·2025
Instance-Based Discovery of ItemSBs Leveraging Individuality Through Discretization
2024
An estrogen receptor signaling transcriptional program linked to immune evasion in human hormone receptor-positive breast cancer
2024· 1 citedOpen Access
Richter transformation acquiring <i>PLCG2</i> mutation during Bruton tyrosine kinase inhibitors treatment
eJHaem·2024· 3 citedOpen Access
TRPV4 channels promote vascular permeability in retinal vascular disease
Experimental Eye Research·2023· 19 cited
Evaluation of a simultaneous adsorption device for cytokines and platelet–neutrophil complexes in vitro and in a rabbit acute lung injury model
Intensive Care Medicine Experimental·2021· 3 citedOpen Access
Evaluation of A Simultaneous Adsorption Device For Cytokines And Neutrophil-Platelet Complexes In Vitro And In A Lung-Protective Ventilated Rabbit Acute Lung Injury Model
Research Square (Research Square)·2021Open Access
Publisher Correction: Colchicine acts selectively in the liver to induce hepatokines that inhibit myeloid cell activation
Nature Metabolism·2021· 1 citedOpen Access
Colchicine acts selectively in the liver to induce hepatokines that inhibit myeloid cell activation
Nature Metabolism·2021· 92 citedOpen Access
Pancreatic glycoprotein 2 is a first line of defense for mucosal protection in intestinal inflammation
Nature Communications·2021· 59 citedOpen Access
shinyDepMap, a tool to identify targetable cancer genes and their functional connections from Cancer Dependency Map data
eLife·2021· 88 citedOpen Access
Author response: shinyDepMap, a tool to identify targetable cancer genes and their functional connections from Cancer Dependency Map data
2021· 1 citedOpen Access
Orally desensitized mast cells form a regulatory network with Treg cells for the control of food allergy
Mucosal Immunology·2020· 32 citedOpen Access
Mesenchymal subtype neuroblastomas are addicted to TGF-βR2/HMGCR-driven protein geranylgeranylation
Scientific Reports·2020· 6 citedOpen Access
A tool for browsing the Cancer Dependency Map reveals functional connections between genes and helps predict the efficacy and selectivity of candidate cancer drugs
2019· 16 citedOpen Access
Human Pluripotency Is Initiated and Preserved by a Unique Subset of Founder Cells
Cell·2019· 48 cited
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Frequent Co-authors

Brent R. Stockwell(13), Satoshi Kimura(10), Rachid Skouta(7), Shinichi Oka(6), Wan Seok Yang(5), Kenji Momota(5), Toshinori Ohmine(5), Hajime Goto(5), Miki Hayano(4), Yoshihiro Hirabayashi(4), Makoto Koizumi(4), Hidehiko Furukawa(4), Toshinori Agatsuma(4), Takashi Nishigaki(4), Junko Sone(4), Shinya Tsutsumi(4), Toshiyuki Kosaka(4), Kazuya Hashinaka(4), Stuart L. Schreiber(3), Hitoshi Hotoda(3)