Daniel C. Tanner

Deciphera Pharmaceuticals (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index481citations15works1.02yr avg
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Research Topics

RNA Research and Splicing(6), Neuroscience and Neuropharmacology Research(4), RNA regulation and disease(3), MicroRNA in disease regulation(2), Melanoma and MAPK Pathways(2)

Publications15 total

Abstract 593: DCC-3084, a brain penetrant RAF dimer inhibitor, broadly inhibits BRAF class I, II, and III alterations leading to growth inhibition of intracranially implanted tumors in preclinical models
Cancer Research·2024· 1 cited
Abstract 4045: DCC-3084, a RAF dimer inhibitor, broadly inhibits BRAF class I, II, III, BRAF fusions, and RAS-driven solid tumors leading to tumor regression in preclinical models
Cancer Research·2023· 4 cited
Abstract 4033: Pan-exon mutant KIT inhibitor DCC-3009 demonstrates tumor regressions in preclinical gastrointestinal stromal tumor models
Cancer Research·2023
cFLIP is critical for oligodendrocyte protection from inflammation
Cell Death and Differentiation·2015· 12 citedOpen Access
KSRP Modulation of GAP-43 mRNA Stability Restricts Axonal Outgrowth in Embryonic Hippocampal Neurons
PLoS ONE·2013· 47 citedOpen Access
Increased Expression of Axogenesis-Related Genes and Mossy Fibre Length in Dentate Granule Cells from Adult HuD Overexpressor Mice
ASN NEURO·2011· 30 citedOpen Access
Oligodendrocyte Progenitors Reversibly Exit the Cell Cycle and Give Rise to Astrocytes in Response to Interferon-γ
Journal of Neuroscience·2011· 50 citedOpen Access
Alterations in mossy fiber physiology and GAP‐43 expression and function in transgenic mice overexpressing HuD
Hippocampus·2008· 25 citedOpen Access
Coordinated Expression of HuD and GAP-43 in Hippocampal Dentate Granule Cells During Developmental and Adult Plasticity
Neurochemical Research·2007· 41 cited
Associative and spatial learning and memory deficits in transgenic mice overexpressing the RNA-binding protein HuD
Neurobiology of Learning and Memory·2006· 72 cited
GAP‐43 in Neural Development and Plasticity
2006· 7 cited
Behavioral Teratogenicity Induced by Nonforced Maternal Nicotine Consumption
Neuropsychopharmacology·2006· 104 citedOpen Access
<i>In vivo</i> post‐transcriptional regulation of GAP‐43 mRNA by overexpression of the RNA‐binding protein HuD
Journal of Neurochemistry·2006· 61 cited
GAP-43 in Neural Development and Plasticity
2006· 5 cited
Fetal Alcohol Exposure Alters GAP‐43 Phosphorylation and Protein Kinase C Responses to Contextual Fear Conditioning in the Hippocampus of Adult Rat Offspring
Alcoholism Clinical and Experimental Research·2004· 22 cited

Frequent Co-authors

Nora I. Perrone‐Bizzozero(8), Federico Bolognani(6), Stacie L. Bulfer(3), Bertrand Le Bourdonnec(3), Gada Al-Ani(3), Joshua W. Large(3), Kylie Luther(3), Yeni K. Romero(3), Forrest A. Stanley(3), Hanumaiah Telikepalli(3), Bryan D. Smith(3), Daniel L. Flynn(3), Shenfeng Qiu(2), Edwin J. Weeber(2), Yu Mi Ahn(2), Chase K. Crawley(2), Cale L. Heiniger(2), Molly M. Hood(2), Salim Javed(2), Cynthia B. Leary(2)