Lawrence A. Kelley

Jackson Laboratory — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index20.0kcitations57works0.02yr avg
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Research Topics

Protein Structure and Dynamics(22), Machine Learning in Bioinformatics(19), Genomics and Phylogenetic Studies(16), RNA and protein synthesis mechanisms(15), Enzyme Structure and Function(13)

Publications57 total

QLTI-16. Feasibility and utility of upfront methylation array testing and multidisciplinary genomic tumor boards
Neuro-Oncology·2025Open Access
Challenges in the return of molecular tumor profiling results
JNCI Journal of the National Cancer Institute·2025
Le mieux est l'enemi du bon. Homology modelling with <i>Phyre2</i> in a deep learning world
Acta Crystallographica Section A Foundations and Advances·2021
The Genome3D Consortium for Structural Annotations of Selected Model Organisms
Methods in molecular biology·2020· 12 cited
Genome3D: integrating a collaborative data pipeline to expand the depth and breadth of consensus protein structure annotation
Nucleic Acids Research·2019· 14 citedOpen Access
PhyreRisk: A Dynamic Web Application to Bridge Genomics, Proteomics and 3D Structural Data to Guide Interpretation of Human Genetic Variants
Journal of Molecular Biology·2019· 29 citedOpen Access
Phyre and PhyreRisk – Integrating genetic variant data with experimental and predicted protein structures and their complexes
EasyChair preprint·2018· 2 citedOpen Access
Identification of the Autochaperone Domain in the Type Va Secretion System (T5aSS): Prevalent Feature of Autotransporters with a β-Helical Passenger
Frontiers in Microbiology·2018· 20 citedOpen Access
ePlant: Visualizing and Exploring Multiple Levels of Data for Hypothesis Generation in Plant Biology
The Plant Cell·2017· 495 citedOpen Access
Fold Recognition
2017· 1 cited
PhyreStorm: A Web Server for Fast Structural Searches Against the PDB
Journal of Molecular Biology·2015· 15 citedOpen Access
Three-dimensional structure of the human breast cancer resistance protein (BCRP/ABCG2) in an inward-facing conformation
Acta Crystallographica Section D Biological Crystallography·2015· 36 citedOpen Access
Partial protein domains: evolutionary insights and bioinformatics challenges
Genome Biology·2015· 16 citedOpen Access
The Phyre2 web portal for protein modeling, prediction and analysis
Nature Protocols·2015· 10.1k citedOpen Access
FoldSynth: Interactive 2D/3D Visualisation Platform for Molecular Strands
Eurographics·2015· 4 citedOpen Access
Genome3D: exploiting structure to help users understand their sequences
Nucleic Acids Research·2014· 55 citedOpen Access
SuSPect: Enhanced Prediction of Single Amino Acid Variant (SAV) Phenotype Using Network Features
Journal of Molecular Biology·2014· 260 citedOpen Access
Validating a Coarse-Grained Potential Energy Function through Protein Loop Modelling
PLoS ONE·2013· 14 citedOpen Access
An analysis of the duplicate testing strategy of an <scp>I</scp>rish immunochemical faecal occult blood test colorectal cancer screening programme
Colorectal Disease·2013· 7 cited
High–quality protein backbone reconstruction from alpha carbons using Gaussian mixture models
Journal of Computational Chemistry·2013· 65 cited
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Frequent Co-authors

Michael J.E. Sternberg(34), Robert M. MacCallum(8), David T. Jones(6), Stefans Mezulis(4), Benjamin R. Jefferys(4), Ian Sillitoe(4), Tom L. Blundell(4), Daniel Buchan(4), Julian Gough(4), Alexey G. Murzin(4), Mark N. Wass(3), Michael J. Sutcliffe(3), Ioannis Filippis(3), Antonina Andreeva(3), Sameer Velankar(3), Christine Orengo(3), Alessia David(3), Stephen Muggleton(3), William Latham(3), Stephen Todd(3)