Simona Parrinello

CRUK Lung Cancer Centre of Excellence — United Kingdom

Medicine · Health Sciences

27h-index7.9kcitations65works3.12yr avg
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Research Topics

Glioma Diagnosis and Treatment(15), Nerve injury and regeneration(10), Neurogenesis and neuroplasticity mechanisms(9), Axon Guidance and Neuronal Signaling(9), MicroRNA in disease regulation(8)

Publications65 total

Microenvironmental TGF-β is an early driver of NF1-associated tumor formation
Cell Reports·2026Open Access
Dual targeting of EphAs and KDR axis hampers VEGF-induced angiogenesis and glioma stem cell replication
Biochemical Pharmacology·2025· 1 citedOpen Access
OS05.3.A AXONAL INJURY IS A TARGETABLE DRIVER OF GLIOBLASTOMA PROGRESSION
Neuro-Oncology·2025Open Access
DEVELOPING A NOVEL HUMAN MODEL OF MINIMAL RESIDUAL DISEASE IN GLIOBLASTOMA
Neuro-Oncology·2025Open Access
Axonal injury is a targetable driver of glioblastoma progression
Nature·2025· 10 citedOpen Access
Microenvironmental TGF-β is an early driver of NF1-associated tumour formation
2025Open Access
Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies
Immunity·2025· 2 citedOpen Access
Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies
Immunity·2025· 16 citedOpen Access
Detecting glioblastoma infiltration beyond conventional imaging tumour margins using MTE-NODDI
Imaging Neuroscience·2025· 1 citedOpen Access
P02.01.B 3-PHOTON IN VIVO IMAGING REVEALS BREAKDOWN OF MICROGLIA SURVEILLANCE UPON GLIOMA INVASION IN THE CORPUS CALLOSUM
Neuro-Oncology·2024Open Access
Dynamics of microglia-glioblastoma crosstalk at the far infiltration zone
2024· 2 citedOpen Access
Generation of immunocompetent somatic glioblastoma mouse models through in situ transformation of subventricular zone neural stem cells
STAR Protocols·2024· 8 citedOpen Access
Dynamics of Microglia-Glioblastoma Crosstalk at the Far Infiltration Zone
SSRN Electronic Journal·2024Open Access
What approaches are needed to understand human development and disease?
Developmental Cell·2023
Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin
Cell Reports·2023· 48 citedOpen Access
Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells
Developmental Cell·2023· 8 citedOpen Access
Data-driven spatio-temporal modelling of glioblastoma
Royal Society Open Science·2023· 5 citedOpen Access
Injury primes mutation-bearing astrocytes for dedifferentiation in later life
Current Biology·2023· 16 citedOpen Access
Data-driven spatio-temporal modelling of glioblastoma
arXiv (Cornell University)·2022Open Access
Injury programs shape glioblastoma
Trends in Neurosciences·2022· 17 citedOpen Access
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Frequent Co-authors

Melanie Clements(22), Samuel Marguerat(14), Judith Campisi(9), Steven M. Pollard(9), Claudia Garcia-Diaz(9), Alison C. Lloyd(8), Lucy Brooks(7), Holly Simpson Ragdale(7), Ana Krtolica(6), Jemima J. Burden(5), Felipe Gálvez‐Cancino(5), Federico Roncaroli(5), Sara Castro Devesa(5), Wenhao Tang(5), Gordon Beattie(5), Ciaran Scott Hill(5), Ilaria Napoli(4), Ian J. White(4), Gillian Morrison(4), Sebastian Brandner(4)