Ana Krtolica

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index11.0kcitations77works0.02yr avg
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Research Topics

Pluripotent Stem Cells Research(24), Cancer, Hypoxia, and Metabolism(21), Telomeres, Telomerase, and Senescence(14), Renal and related cancers(10), Cancer Research and Treatments(10)

Publications74 total

Microvascular response of an oxygen carrier in the penumbral tissue of fast and slow progressors in a canine large vessel occlusion model
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2024
Double blind trial of a deuterated form of linoleic acid (RT001) in Friedreich ataxia
Journal of Neurology·2022· 12 cited
Kinetic Evaluation of the Hypoxia Radiotracers [18F]FMISO and [18F]FAZA in Dogs with Spontaneous Tumors Using Dynamic PET/CT Imaging
Nuclear Medicine and Molecular Imaging·2022· 7 citedOpen Access
Novel Oxygen Carrier Slows Infarct Growth in Large Vessel Occlusion Dog Model Based on Magnetic Resonance Imaging Analysis
Stroke·2022· 10 citedOpen Access
E-023 Intravenous oxygen carrier therapy delays infarct size progression in a canine large vessel occlusion model
2020Open Access
Correction: Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic
PLoS Biology·2019· 2 citedOpen Access
TMIC-15. OMX IS A TUMOR MICROENVIRONMENT MODIFIER THAT RESTORES ANTI-TUMOR IMMUNITY AND IMPROVES ANTI-TUMOR EFFICACY BY REDUCING TUMOR HYPOXIA IN INTRACRANIAL GLIOBLASTOMA MOUSE MODEL
Neuro-Oncology·2018Open Access
Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic
PLoS Biology·2018· 23 citedOpen Access
Abstract 4726A: The oxygen carrier omx restores antitumor immunity and cures tumors as a single agent or in combination with checkpoint inhibitors in an intracranial glioblastoma mouse model
Cancer Research·2018· 2 cited
Abstract 1744: Reversal of advanced colitis-associated colon cancer by OMX, a novel oxygen carrier that immunosensitizes the hypoxic tumor microenvironment
Cancer Research·2018
Abstract 4686: Omx a hypoxia modulator reverses the immunosuppressive glioblastoma microenvironment by stimulating T cell infiltration and activation that results in increased number of long-term survivors
Cancer Research·2017· 5 cited
Abstract 1627: Enhancement of anti-cancer immunity by OMX, a novel oxygen carrier immunotherapeutic that ameliorates the hypoxic tumor microenvironment
Cancer Research·2017
A New Paradigm in Protecting Ischemic Brain: Preserving the Neurovascular Unit Before Reperfusion
Springer series in translational stroke research·2017· 5 cited
Abstract 14081: Preservation of Myocardial Cotractility During Acute Hypoxia With OMX, a Novel Oxygen Delivery Biotherapeutic
Circulation·2016
IMST-52. OMX, AN IND-STAGE BROAD-ACTING OXYGEN CARRIER, IMMUNOSENSITIZES THE TUMOR MICROENVIRONMENT AND PROMOTES EFFECTOR T CELL RESPONSES IN THE GL261 INTRACRANIAL SYNGENEIC GLIOBLASTOMA MODEL
Neuro-Oncology·2016Open Access
Abstract B029: OMX: An oxygen carrier biotherapeutic that ameliorates the hypoxic tumor microenvironment and promotes anticancer T cell activity
Cancer Immunology Research·2016
Abstract 2790: Sensitizing the hypoxic tumor microenvironment with OMX, a breakthrough oxygen delivery protein: From protein engineering to clinical trial
Cancer Research·2016
Abstract 67: Novel and Safe Oxygen Carrier Prevents Brain Damage After Focal Ischemia and Improves Functional Outcomes
Stroke·2016· 1 cited
NIMG-45REAL-TIME PET IMAGING DEMONSTRATES TUMOR ACCUMULATION AND OXYGENATION BY OMX-4.80P, AN OXYGEN CARRIER ENGINEERED FOR THE TREATMENT OF GLIOBLASTOMA
Neuro-Oncology·2015Open Access
ATPS-49RESULTS OF A PHASE 0 CLINICAL TRIAL IN CANINE BRAIN CANCER EVALUATING SAFETY AND ACTIVITY OF OMX-4.80P, A PROTEIN OXYGEN CARRIER IND CANDIDATE FOR TREATMENT OF GLIOBLASTOMA
Neuro-Oncology·2015Open Access
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Frequent Co-authors

Judith Campisi(12), Olga Genbačev(12), Natacha Le Moan(11), Duško Ilić(10), Stephen P. Cary(10), Susan J. Fisher(9), Jonathan A. Winger(7), Simona Parrinello(6), Tamara Zdravkovic(6), G. Giritharan(6), Tina Davis(6), Jean‐Philippe Coppé(5), John W. Ludlow(5), Kevin Tanaka(5), Carlos Simón(4), Philberta Leung(4), Sarah Ng(4), Laura Serwer(4), Catherine Bédard(4), Pierre‐Yves Desprez(3)