Michael A. Kalchman

Neuroscience · Life Sciences

11h-index3.1kcitations13works0.02yr avg
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Research Topics

Genetic Neurodegenerative Diseases(13), Mitochondrial Function and Pathology(6), RNA Research and Splicing(3), Ubiquitin and proteasome pathways(3), Muscle Physiology and Disorders(2)

Publications13 total

The isolation and characterization of Huntingtin interacting proteins
Open Collections·2009Open Access
Forskolin and dopamine D1 receptor activation increase Huntingtin's association with endosomes in immortalized neuronal cells of striatal origin
Neuroscience·1999· 44 cited
The Influence of Huntingtin Protein Size on Nuclear Localization and Cellular Toxicity
The Journal of Cell Biology·1998· 313 citedOpen Access
HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain
Nature Genetics·1997· 383 cited
Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
Nature Genetics·1996· 577 cited
Huntingtin Is Ubiquitinated and Interacts with a Specific Ubiquitin-conjugating Enzyme
Journal of Biological Chemistry·1996· 363 citedOpen Access
Absence of Disease Phenotype and Intergenerational Stability of the Cag Repeat in Transgenic Mice Expressing the Human Huntington Disease Transcript
Human Molecular Genetics·1996· 112 cited
Structural analysis of the 5′ region of mouse and human huntington disease genes reveals conservation of putative promoter region and di- and trinucleotide polymorphisms
Genomics·1995· 38 cited
Comparative analysis of the 5{prime} genomic and promoter regions between the mouse (Hdh) and human Huntington disease (HD) gene
The American Journal of Human Genetics·1994
The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease
Nature Genetics·1993· 1.1k cited
Identification of an Alu retrotransposition event in close proximity to a strong candidate gene for Huntington's disease
Nature·1993· 49 cited
Differential 3′ polyadenylation of the Huntington disease gene results in two mRNA species with variable tissue expression
Human Molecular Genetics·1993· 96 cited
A transcription map of the region containing the Huntington disease gene
Human Molecular Genetics·1993· 40 cited

Frequent Co-authors

Michael R. Hayden(11), Y. Paul Goldberg(8), Rona K. Graham(6), Jamal Nasir(6), Biaoyang Lin(4), Hiroshi Koide(4), Susan E. Andrew(3), Martina Metzler(3), Jane Theilmann(2), Elizabeth Starr(2), Parsa Kazemi‐Esfarjani(2), Krista McCutcheon(2), Cheryl L. Wellington(2), R D Gietz(2), Jutta Zeisler(2), B. Lin(2), Johanna M. Rommens(2), Gordon B. Hutchinson(2), Rona Graham(2), Martha L. Glaves(2)