Natasha C. Lucki

Thermo Fisher Scientific (United States) — United States

Medicine · Health Sciences

14h-index928citations23works0.02yr avg
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Research Topics

Cholesterol and Lipid Metabolism(9), Sphingolipid Metabolism and Signaling(8), Estrogen and related hormone effects(6), Hormonal Regulation and Hypertension(6), Sports Performance and Training(3)

Publications23 total

STEM-20. A CANCER STEM CELL-SELECTIVE APOPTOSIS-INDUCING SMALL MOLECULE FOR THE TREATMENT OF GBM
Neuro-Oncology·2020Open Access
A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer
Proceedings of the National Academy of Sciences·2019· 35 citedOpen Access
High-Titer Recombinant Protein Production
Genetic Engineering & Biotechnology News·2018· 5 cited
ExpiSf™: A chemically-defined baculovirus-based expression system for enhanced Protein production in Sf9 cells
2018
Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers
Proceedings of the National Academy of Sciences·2016· 332 citedOpen Access
Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2013· 22 citedOpen Access
cAMP-stimulated phosphorylation of diaphanous 1 regulates protein stability and interaction with binding partners in adrenocortical cells
Molecular Biology of the Cell·2013· 18 cited
Acid Ceramidase (ASAH1) Represses Steroidogenic Factor 1-Dependent Gene Transcription in H295R Human Adrenocortical Cells by Binding to the Receptor
Molecular and Cellular Biology·2012· 27 citedOpen Access
Acid Ceramidase Represses Steroidogenic Factor 1‐dependent Gene Transcription by Binding to the Receptor in the Nucleus of H295R Human Adrenocortical Cells
The FASEB Journal·2012
Acid Ceramidase (ASAH1) Is a Global Regulator of Steroidogenic Capacity and Adrenocortical Gene Expression
Molecular Endocrinology·2012· 37 citedOpen Access
Characterization of the role of acid ceramidase in adrenocortical steroid hormone biosynthesis
SMARTech Repository (Georgia Institute of Technology)·2011
Sphingosine-1-phosphate rapidly increases cortisol biosynthesis and the expression of genes involved in cholesterol uptake and transport in H295R adrenocortical cells
Molecular and Cellular Endocrinology·2011· 42 citedOpen Access
Genistein Stimulates MCF-7 Breast Cancer Cell Growth by Inducing Acid Ceramidase (ASAH1) Gene Expression
Journal of Biological Chemistry·2011· 94 citedOpen Access
Nuclear Sphingolipid Metabolism
Annual Review of Physiology·2011· 79 cited
Genistein Regulates Ceramide Metabolism by Inducing Acid Ceramidase Expression in MCF‐7 Breast Cancer Cells
The FASEB Journal·2010
The interplay between bioactive sphingolipids and steroid hormones
Steroids·2010· 62 citedOpen Access
The cAMP-responsive element binding protein (CREB) regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2009· 26 citedOpen Access
Multiple Roles for Sphingolipids in Steroid Hormone Biosynthesis
Sub-cellular biochemistry/Subcellular biochemistry·2008· 75 citedOpen Access
ACTH/cAMP regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells
The FASEB Journal·2008
Grip strength and endurance throughout the menstrual cycle in eumenorrheic and women using oral contraceptives
International Journal of Industrial Ergonomics·2008· 7 cited
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Frequent Co-authors

Marion B. Sewer(14), Justin L. Anglin(3), Luke L. Lairson(3), Christopher W. Nicolay(3), Sibali Bandyopadhyay(3), Elaine Wang(3), Donghui Li(3), Donghui Li(2), Alfred H. Merrill(2), Genaro R. Villa(2), Naja Vergani(2), Michael J. Bollong(2), Brittney A. Beyer(2), Stephan H. Spangenberg(2), Emily N. Chin(2), Amandeep Sharma(2), Kevin C. Johnson(2), Perry Gordon(2), Stephen Skirboll(2), Heiko Wurdak(2)