Thimmasettappa Thippeswamy

Iowa State University — United States

Neuroscience · Life Sciences

27h-index2.2kcitations92works2.32yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(37), Nitric Oxide and Endothelin Effects(15), Pesticide Exposure and Toxicity(14), Epilepsy research and treatment(13), Neuroinflammation and Neurodegeneration Mechanisms(12)

Publications92 total

Current review on inducible nitric oxide synthase and Src tyrosine kinase inhibitors as disease-modifiers in preclinical models of epilepsy.
PubMed·2025
Automated Seizure Detection in Animal EEG Signals
2025Open Access
Organophosphate Chemical Nerve Agents, Oxidative Stress, and NADPH Oxidase Inhibitors: An Overview
International Journal of Molecular Sciences·2025Open Access
Mitigating organophosphate nerve agent, soman (GD), induced long-term neurotoxicity: Saracatinib, a Src Tyrosine Kinase inhibitor, as a potential countermeasure
Journal of Neuroinflammation·2025· 2 citedOpen Access
Off-target effects of the NADPH oxidase inhibitor mitoapocynin-encapsulated nanoparticles and free-drug oral treatment in a rat DFP model of neurotoxicity
Journal of drug targeting·2025· 1 citedOpen Access
Mitigating Organophosphate Nerve Agent, Soman (GD)-Induced Long-Term Neurotoxicity: Saracatinib, a Src Tyrosine Kinase Inhibitor, as a Potential Countermeasure
2025· 1 citedOpen Access
Diet-incorporated saracatinib, a Src tyrosine kinase inhibitor, counteracts diisopropylfluorophosphate (DFP)-induced chronic neurotoxicity in the rat model
Biomedicine & Pharmacotherapy·2025· 4 citedOpen Access
The Effects of Neuronal Fyn Knockdown in the Hippocampus in the Rat Kainate Model of Temporal Lobe Epilepsy
Cells·2025· 2 citedOpen Access
Proinflammatory cytokines, oxidative stress, and organ function as biomarkers of soman (GD) chronic neurotoxicity
Scientific Reports·2025· 6 citedOpen Access
Diet-Incorporated Saracatinib, a Src Tyrosine Kinase Inhibitor, Counteracts Diisopropylfluorophosphate (Dfp)-Induced Chronic Neurotoxicity in the Rat Model
SSRN Electronic Journal·2025Open Access
Diet-Incorporated Saracatinib, a Src Tyrosine Kinase Inhibitor, Counteracts Diisopropylfluorophosphate (Dfp)-Induced Chronic Neurotoxicity in the Rat Model
SSRN Electronic Journal·2025Open Access
Comprehensive Biomarkers of Soman (GD)-induced Chronic Toxicity: Proinflammatory Cytokines, Oxidative Stress, and Organ Function Parameters
2024· 1 citedOpen Access
Enhanced Fyn-tau and NR2B-PSD95 interactions in epileptic foci in experimental models and human epilepsy
Brain Communications·2024· 13 citedOpen Access
Inhibiting Inducible Nitric Oxide Synthase with 1400W Reduces Soman (GD)-Induced Ferroptosis in Long-Term Epilepsy-Associated Neuropathology: Structural and Functional Magnetic Resonance Imaging Correlations with Neurobehavior and Brain Pathology
Journal of Pharmacology and Experimental Therapeutics·2023· 11 citedOpen Access
The NADPH Oxidase Inhibitor, Mitoapocynin, Mitigates DFP-Induced Reactive Astrogliosis in a Rat Model of Organophosphate Neurotoxicity
Antioxidants·2023· 7 citedOpen Access
The effects of Src tyrosine kinase inhibitor, saracatinib, on the markers of epileptogenesis in a mixed-sex cohort of adult rats in the kainic acid model of epilepsy
Frontiers in Molecular Neuroscience·2023· 11 citedOpen Access
Exploring the benefits of in-diet versus repeated oral dosing of saracatinib (AZD0530) in chronic studies: insights into pharmacokinetics and animal welfare
Frontiers in Veterinary Science·2023· 6 citedOpen Access
Disease-modifying effects of a glial-targeted inducible nitric oxide synthase inhibitor (1400W) in mixed-sex cohorts of a rat soman (GD) model of epilepsy
Journal of Neuroinflammation·2023· 21 citedOpen Access
Peripheral and central effects of NADPH oxidase inhibitor, mitoapocynin, in a rat model of diisopropylfluorophosphate (DFP) toxicity
Frontiers in Cellular Neuroscience·2023· 9 citedOpen Access
Disease-Modifying Effects of a Glial-targeted Inducible Nitric Oxide Synthase Inhibitor (1400W) in Mixed-sex Cohorts of a Rat Soman (GD) Model of Epilepsy
Research Square (Research Square)·2023Open Access
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Frequent Co-authors

Richard Morris(15), Marson Putra(13), Meghan Gage(13), Shaunik Sharma(10), Sreekanth Puttachary(9), Jennifer S. McKay(9), John P. Quinn(9), Karen Tse(7), Graeme J. Sills(7), Christina Meyer(7), Suraj S. Vasanthi(6), Edward Beamer(5), Anna Siobhan Cosgrave(5), Nikhil S. Rao(5), Logan Wachter(4), Manikandan Samidurai(4), Emanuele Ricci(3), Anthony G Marson(3), Munir Pirmohamed(3), Chong Wang(3)