Bogdan I. Florea

Leiden University — Netherlands

Biochemistry, Genetics and Molecular Biology · Life Sciences

48h-index7.4kcitations248works5.12yr avg
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Research Topics

Ubiquitin and proteasome pathways(74), Protein Degradation and Inhibitors(46), Peptidase Inhibition and Analysis(45), Glycosylation and Glycoproteins Research(35), Click Chemistry and Applications(31)

Publications248 total

Structural Basis of Substrate Selectivity and Catalysis in the Mycobacterial Long-Chain Acyl-CoA Carboxylase
2026Open Access
Structure-Based Design of Pan-Selective Peptide Epoxyketones for the Three Human Immunoproteasome Active Sites
Journal of Medicinal Chemistry·2026
Phosphate ions modulate enzyme activity and epistatic effects in two clavulanic acid‐resistant β‐lactamase mutants
Protein Science·2025· 2 citedOpen Access
Using BONCAT to dissect the proteome of <i>S. aureus</i> persisters
mSphere·2025Open Access
A Highly Specific Monoacylglycerol Lipase PROTAC Probe
2025Open Access
Carfilzomib-specific proteasome β5/β2 inhibition drives cardiotoxicity via remodeling of protein homeostasis and the renin-angiotensin-system
iScience·2025· 3 citedOpen Access
The Efficiency of the Deposit-Return System in Romania: A Statistical and Comparative Analysis
Proceedings of the ... International Conference on Business Excellence·2025Open Access
Antimicrobial Susceptibility Patterns of Staphylococcus spp. Isolates from Mastitic Cases in Romanian Buffaloes from Western Romania
Antibiotics·2025· 5 citedOpen Access
Influence of Homogenization Heat Treatments on the Mechanical, Structural, Biodegradation, and Cavitation Behavior of Some Alloys in the ZnMg(Fe) System
Crystals·2025Open Access
CellEKT: A Robust Chemical Proteomics Workflow to Profile Cellular Target Engagement of Kinase Inhibitors
Molecular & Cellular Proteomics·2025· 4 citedOpen Access
Using BONCAT To Dissect The Proteome Of <i>S. aureus</i> Persisters
2024Open Access
CellEKT: A robust chemical proteomics workflow to profile cellular target engagement of kinase inhibitors
2024· 1 citedOpen Access
Polymers for Ceramics and Their Use in Ecological Construction Materials
Preprints.org·2024Open Access
Previously Published Phosphatase Probes have Limited Utility Due to their Unspecific Reactivity
ChemBioChem·2024· 4 citedOpen Access
Integrated transcriptomics- and structure-based drug repositioning identifies drugs with proteasome inhibitor properties
Scientific Reports·2024· 2 citedOpen Access
The Impact of ZnO Nanofillers on the Mechanical and Anti-Corrosion Performances of Epoxy Composites
Polymers·2024· 32 citedOpen Access
Human milk oligosaccharide 2’-fucosyllactose protects against high-fat diet-induced obesity by changing intestinal mucus production, composition and degradation linked to changes in gut microbiota and faecal proteome profiles in mice
Gut·2024· 47 citedOpen Access
Immunoproteasomal Inhibition With ONX-0914 Attenuates Atherosclerosis and Reduces White Adipose Tissue Mass and Metabolic Syndrome in Mice
Arteriosclerosis Thrombosis and Vascular Biology·2024· 7 citedOpen Access
Genetic ablation of Lmp2 increases the susceptibility for impaired cardiac function
Frontiers in Molecular Biosciences·2024Open Access
The proteasome modulates endocytosis specifically in glomerular cells to promote kidney filtration
Nature Communications·2024· 6 citedOpen Access
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Frequent Co-authors

Herman S. Overkleeft(38), Martijn Verdoes(9), Wouter A. van der Linden(9), Gijsbert A. van der Marel(9), Hans E. Junginger(7), Mario van der Stelt(7), Lianne I. Willems(7), Alexei F. Kisselev(7), Gerrit Borchard(6), Wouter W. Kallemeijn(6), Johannes M. F. G. Aerts(6), Jeroen D. C. Codée(6), Hans den Dulk(5), Rolf G. Boot(5), Gijsbert A. van der Marel(5), Dmitri V. Filippov(5), Hans van den Elst(5), Annelot C. M. van Esbroeck(4), Marc P. Baggelaar(4), Martin D. Witte(4)