Wouter W. Kallemeijn

The Francis Crick Institute — United Kingdom

Chemistry · Physical Sciences

28h-index2.5kcitations67works0.42yr avg
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Research Topics

Carbohydrate Chemistry and Synthesis(33), Lysosomal Storage Disorders Research(26), Glycosylation and Glycoproteins Research(17), Cellular transport and secretion(11), Protein Kinase Regulation and GTPase Signaling(6)

Publications67 total

GBP1 recruitment to actin-rich pedestals induced by extracellular Gram-negative bacteria promotes pyroptosis
2025Open Access
MYC deregulation sensitizes cancer cells to N-myristoyltransferase inhibition
Cell Reports·2025· 2 citedOpen Access
Chemical proteomic approaches to investigate S-prenylation
Methods in enzymology on CD-ROM/Methods in enzymology·2025
Chemical proteomic approaches to investigate N-myristoylation
Methods in enzymology on CD-ROM/Methods in enzymology·2025
#ECR-Paper-02 Choroideremia iPSC-RPE show an oxidative stress-induced senescent phenotype
2024Open Access
COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells
Nature Cell Biology·2023· 48 citedOpen Access
Bi-allelic <i>ACBD6</i> variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders
Brain·2023· 15 citedOpen Access
Abstract 439: From foe to friend: <i>In vivo</i> reprogramming of tumor-associated macrophages to an anti-cancer phenotype by modulating <i>N</i>-myristoyltransferase activity
Cancer Research·2023
Supplementary Table S1 from Phosphatidylinositol-3-OH Kinase or RAS Pathway Mutations in Human Breast Cancer Cell Lines
2023Open Access
Data from Phosphatidylinositol-3-OH Kinase or RAS Pathway Mutations in Human Breast Cancer Cell Lines
2023Open Access
Data from Phosphatidylinositol-3-OH Kinase or RAS Pathway Mutations in Human Breast Cancer Cell Lines
2023Open Access
Supplementary Table S1 from Phosphatidylinositol-3-OH Kinase or RAS Pathway Mutations in Human Breast Cancer Cell Lines
2023Open Access
Inhibition of host <i>N</i> -myristoylation compromises the infectivity of SARS-CoV-2 due to Golgi-bypassing egress from lysosomes and endoplasmic reticulum
2023· 2 citedOpen Access
Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry
PLoS Pathogens·2022· 28 citedOpen Access
Inhibition of vaccinia virus L1 <i>N</i> -myristoylation by the host <i>N</i> -myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry
2022· 4 citedOpen Access
Proteome-wide analysis of protein lipidation using chemical probes: in-gel fluorescence visualization, identification and quantification of N-myristoylation, N- and S-acylation, O-cholesterylation, S-farnesylation and S-geranylgeranylation
Nature Protocols·2021· 51 citedOpen Access
Targeting methionine aminopeptidase 2 in cancer, obesity, and autoimmunity
Trends in Pharmacological Sciences·2021· 43 citedOpen Access
The Uncovered Function of the Drosophila GBA1a-Encoded Protein
Cells·2021· 8 citedOpen Access
Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins
Nature Communications·2020· 55 citedOpen Access
Novel defect in phosphatidylinositol 4‐kinase type 2‐alpha (<scp><i>PI4K2A</i></scp>) at the membrane‐enzyme interface is associated with metabolic cutis laxa
Journal of Inherited Metabolic Disease·2020· 10 citedOpen Access
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Frequent Co-authors

Johannes M. F. G. Aerts(36), Herman S. Overkleeft(30), Rolf G. Boot(20), Jeroen D. C. Codée(16), Martin D. Witte(15), Bogdan I. Florea(11), Jianbing Jiang(11), Gijsbert A. van der Marel(10), Saskia Scheij(9), Edward W. Tate(9), Kah‐Yee Li(8), Roelof Ottenhoff(8), Lianne I. Willems(8), Thomas J. M. Beenakker(7), Wilma E. Donker‐Koopman(6), Hans van den Elst(6), Marthe T. C. Walvoort(6), Jan Aten(5), Gijsbert A. van der Marel(5), André R. A. Marques(5)