Barbara K. Klein

Utrecht University — Netherlands

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index1.0kcitations32works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

RNA and protein synthesis mechanisms(9), Bacterial Genetics and Biotechnology(8), Immune Cell Function and Interaction(6), Immune Response and Inflammation(5), Cytokine Signaling Pathways and Interactions(5)

Publications32 total

Can low-level features explain numerosity tuning, or do interference effects reveal how numerosity is computed?
Journal of Vision·2014Open Access
Characterization of dendritic cells generated in vivo by an E. coli derived chimeric dual receptor agonist.
PubMed·2002
Progenipoietin‐generated dendritic cells exhibit anti‐tumor efficacy in a therapeutic murine tumor model
International Journal of Cancer·2002· 7 cited
Receptor Binding Kinetics of Human IL-3 Variants with Altered Proliferative Activity
Biochemical and Biophysical Research Communications·2001· 12 cited
Modulation of the Binding Affinity of Myelopoietins for the Interleukin-3 Receptor by the Granulocyte Colony-Stimulating Factor Receptor Agonist
Biochemistry·2001· 4 cited
In Vitro Interleukin-3 Binding to Leukemia Cells Predicts Cytotoxicity of a Diphtheria Toxin/IL-3 Fusion Protein
Bioconjugate Chemistry·2000· 24 cited
Use of combinatorial mutagenesis to select for multiply substituted human interleukin-3 variants with improved pharmacologic properties
Experimental Hematology·1999· 16 cited
Circular Permutation of the Granulocyte Colony-Stimulating Factor Receptor Agonist Domain of Myelopoietin
Biochemistry·1999· 24 cited
Interleukin-6 receptor signaling. I. gp80 and gp130 receptor interaction in the absence of interleukin-6.
PubMed·1999· 10 cited
The Receptor Binding Site of Human Interleukin-3 Defined by Mutagenesis and Molecular Modeling
Journal of Biological Chemistry·1997· 35 citedOpen Access
Interleukin-6 receptor antagonists inhibit interleukin-11 biological activity.
PubMed·1997· 4 cited
Three-dimensional Solution Structure and Backbone Dynamics of a Variant of Human Interleukin-3
Journal of Molecular Biology·1996· 74 cited
HUMAN INTERLEUKIN 3 (IL-3) MUTANT WITH TRUNCATION AT BOTH N-AND C-TERMINI AND 14 RESIDUE CHANGES, NMR, MINIMIZED AVERAGE STRUCTURE
1995
Saturation Mutagenesis of Human Interleukin-3
Journal of Biological Chemistry·1995· 45 citedOpen Access
1H, 13C, and 15N NMR Resonance Assignments, Secondary Structure, and Backbone Topology of a Variant of Human Interleukin-3
Biochemistry·1995· 25 cited
Potent interleukin 3 receptor agonist with selectively enhanced hematopoietic activity relative to recombinant human interleukin 3.
Proceedings of the National Academy of Sciences·1995· 56 cited
Three Different cDNAs Encoding Acyl Carrier Proteins from Cuphea lanceolata
PLANT PHYSIOLOGY·1994· 19 citedOpen Access
Effects of signal peptide changes on the secretion of bovine somatotropin (bST) from <i>Escherichia coli</i>
Protein Engineering Design and Selection·1992· 9 cited
Secretion of Active Bovine Somatotropin in Escherichia coli
Nature Biotechnology·1991· 15 cited
Production of bovine insulin-like growth factor 2 (bIGF2) in Escherichia coli
Gene·1991· 9 cited
page 1 of 2Next →

Frequent Co-authors

John P. McKearn(7), Charles A. McWherter(5), William F. Hood(5), Kumnan Paik(5), Joseph O. Polazzi(5), David Schlessinger(5), S. Christopher Bauer(4), Yiqing Feng(4), Peter O. Olins(4), Jeng‐Jong Shieh(4), Joseph K. Welply(4), Ramnath Seetharam(3), Sarah R. Braford(3), Claire E. Kotts(3), Alan M. Easton(3), Guy della-Cioppa(2), Dilip M. Shah(2), Robert T. Fraley(2), Ganesh M. Kishore(2), Robert A. Heeren(2)