David Schlessinger

National Institute on Aging — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

105h-index65.4kcitations530works1.02yr avg
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Research Topics

RNA and protein synthesis mechanisms(126), RNA modifications and cancer(83), Genetic Associations and Epidemiology(60), Bacterial Genetics and Biotechnology(42), DNA and Nucleic Acid Chemistry(34)

Publications507 total

Reduced cyclin D3 expression in erythroid cells protects against malaria
Nature·2026· 1 citedOpen Access
Author response: KDM5 demethylases suppress R-loop-mediated ‘viral mimicry’ and DNA damage in breast cancer cells
2025Open Access
KDM5 demethylases suppress R-loop-mediated ‘viral mimicry’ and DNA damage in breast cancer cells
eLife·2025Open Access
Analysis of a Novel Human Protein, ORF3, Encoded by Spacer rDNA
Journal of Molecular Evolution·2025Open Access
<scp><i>TYK2</i></scp>:<scp>p.Pro1104Ala</scp> Variant Protects Against Autoimmunity by Modulating Immune Cell Levels
Immunology·2025· 1 citedOpen Access
TYK2:p.Pro1104Ala variant protects against autoimmunity by modulating immune cell levels
2024
Vascular density normative data of radial peripapillary capillary plexus in healthy Caucasian subjects
Graefe s Archive for Clinical and Experimental Ophthalmology·2024· 2 citedOpen Access
A large-scale screening identified in USH2A gene the P3272L founder pathogenic variant explaining familial Usher syndrome in Sardinia, Italy
BMC Ophthalmology·2024· 1 citedOpen Access
Identifying Pre-sepsis Opportunities for Risk Stratification in Diverse Healthcare Venues
2024
Comparative analysis and classification of highly divergent mouse rDNA units based on their intergenic spacer (IGS) variability
NAR Genomics and Bioinformatics·2024· 3 citedOpen Access
Transcriptome organization of white blood cells through gene co-expression network analysis in a large RNA-seq dataset
Frontiers in Immunology·2024· 2 citedOpen Access
Genetic and biomarker modulation of arterial stiffness change in the SardiNIA population cohort
Frontiers in Epidemiology·2024· 1 citedOpen Access
Development and External Validation of a Prediction Model for Colorectal Cancer Among Patients Awaiting Surveillance Colonoscopy Following Polypectomy
Gastro Hep Advances·2024· 3 citedOpen Access
Glucose-6-phosphate dehydrogenase deficiency accelerates arterial aging in diabetes
Acta Diabetologica·2023· 3 citedOpen Access
Echocardiographic heart ageing patterns predict cardiovascular and non-cardiovascular events and reflect biological age: the SardiNIA study
European Journal of Preventive Cardiology·2023· 18 citedOpen Access
EDA ligand triggers plasma membrane trafficking of its receptor EDAR via PKA activation and SNAP23-containing complexes
Cell & Bioscience·2023· 1 citedOpen Access
Effect of Genetic Factors, Age and Sex on Levels of Circulating Extracellular Vesicles and Platelets
International Journal of Molecular Sciences·2023· 7 citedOpen Access
Actively transcribed rDNA and distal junction (DJ) sequence are involved in association of NORs with nucleoli
Cellular and Molecular Life Sciences·2023· 6 citedOpen Access
Development and Validation of a Diabetic Retinopathy Risk Stratification Algorithm
2023Open Access
Development and Validation of a Diabetic Retinopathy Risk Stratification Algorithm
2023Open Access
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Frequent Co-authors

Gonçalo R. Abecasis(22), Manuela Uda(22), Serena Sanna(22), Sandra Lai(12), Fabio Busonero(11), Ramaiah Nagaraja(11), Andrea Maschio(11), Antonella Mulas(11), Mariano Dei(10), Antonio Cao(10), Francesco Cucca(9), Luigi Ferrucci(9), Gianluca Usala(9), Silvia Naitza(9), Edward G. Lakatta(8), Christian Gieger(8), Carlo Sidore(7), Angelo Scuteri(7), John C. Chambers(6), Toshiko Tanaka(6)