Yiqun Chang

University of Sydney — Australia

Computer Science · Physical Sciences

15h-index656citations35works2.42yr avg
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Research Topics

Computational Drug Discovery Methods(9), Bacterial biofilms and quorum sensing(7), Antibiotic Resistance in Bacteria(4), Synthesis and biological activity(3), Analytical Chemistry and Chromatography(3)

Publications35 total

Corrigendum to ‘Novel ligustilide derivatives target quorum sensing system LasR/LasB and relieve inflammatory response against Pseudomonas aeruginosa infection’ [Eur J Med Chem. 263 (2024) 115972]
European Journal of Medicinal Chemistry·2025Open Access
Identification of ferredoxin PA1551 as an antibacterial synergistic target for biofilm inhibitors against Pseudomonas aeruginosa
npj Biofilms and Microbiomes·2025Open Access
Hollow Cu/Pt Interspersed GO Nanosheets Cascade Triggering Catalytic Signal Amplification for Colorimetric/SERS Sensing of <i>Klebsiella pneumoniae</i> in Clinical Samples
Analytical Chemistry·2025· 2 cited
Identification of ferredoxin PA1551 in the bacterial iron uptake pathway and exploration of its antibacterial synergistic as target for biofilm inhibitors against Pseudomonas aeruginosa infection
2025Open Access
An mRNA-display derived cyclic peptide scaffold reveals the substrate binding interactions of an N-terminal cysteine oxidase
Nature Communications·2025· 7 citedOpen Access
Molecular mechanism of androgen receptor mutation in multigenerational mild androgen insensitivity syndrome
Endocrine Connections·2024Open Access
Novel benzothiazole derivatives target the Gac/Rsm two-component system as antibacterial synergists against Pseudomonas aeruginosa infections
Acta Pharmaceutica Sinica B·2024· 8 citedOpen Access
Discovery of <i>N</i>‐(phenylsulfonyl)thiazole‐2‐carboxamides as potent <i>α</i>‐glucosidase inhibitors
Drug Development Research·2023· 4 citedOpen Access
Novel ligustilide derivatives target quorum sensing system LasR/LasB and relieve inflammatory response against Pseudomonas aeruginosa infection
European Journal of Medicinal Chemistry·2023· 17 cited
A Guide to In Silico Drug Design
Pharmaceutics·2022· 197 citedOpen Access
New <i>Pqs</i> Quorum Sensing System Inhibitor as an Antibacterial Synergist against Multidrug-Resistant <i>Pseudomonas aeruginosa</i>
Journal of Medicinal Chemistry·2021· 55 cited
Virtual Screening and Biological Evaluation of Anti-Biofilm Agents Targeting LuxS in the Quorum Sensing System
Natural Product Communications·2021· 11 citedOpen Access
Design, synthesis and evaluation of halogenated furanone derivatives as quorum sensing inhibitors in Pseudomonas aeruginosa
European Journal of Pharmaceutical Sciences·2019· 57 cited
Insights into the c-Jun N-terminal kinase 3 (JNK3) inhibitors: CoMFA, CoMSIA analyses and molecular docking studies
Medicinal Chemistry Research·2019· 3 cited
A strategy for screening trypsin inhibitors from traditional Chinese medicine based on a monolithic capillary immobilized enzyme reactor coupled with offline liquid chromatography and mass spectrometry
Journal of Separation Science·2019· 18 cited
Hybrids of arenobufagin and benzoisoselenazol reducing the cardiotoxicity of arenobufagin
Bioorganic & Medicinal Chemistry Letters·2018· 6 cited
QSAR Studies on Thiazole Derivatives as HCV NS5A Inhibitors via CoMFA and CoMSIA Methods
Letters in Drug Design & Discovery·2018· 1 citedOpen Access
DNA colorimetric logic gate in microfluidic chip based on unmodified gold nanoparticles and molecular recognition
Sensors and Actuators B Chemical·2018· 27 cited
Strigolactones: a plant phytohormone as novel anti-inflammatory agents
MedChemComm·2017· 20 citedOpen Access
4-arylamidobenzyl substituted 5-bromomethylene-2(5 H )-furanones for chronic bacterial infection
European Journal of Medicinal Chemistry·2017· 16 cited
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Frequent Co-authors

Pinghua Sun(18), Wei‐Min Chen(13), Jing Lin(9), Jialiang Guo(8), Junxia Zheng(7), Haibo Zhou(6), Jun Liu(6), Pinghua Sun(5), Siyu Zhao(5), Jinsong Hou(4), Guochao Liao(4), Shu‐Meng Jiao(4), Hai-Chuan Xiao(4), Jun Xu(4), Gaokeng Xiao(4), Jonathan J. Du(3), David E. Hibbs(3), Zhiying Miao(3), Zhengjin Jiang(3), Cheng-Kang Peng(3)