Paul J. Beresford

Helix Biomedix (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index2.9kcitations17works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Cell death mechanisms and regulation(7), RNA Interference and Gene Delivery(6), Mechanisms of cancer metastasis(4), DNA Repair Mechanisms(3), HIV Research and Treatment(2)

Publications17 total

Minimum Technical Data Elements for Liquid Biopsy Data Submitted to Public Databases
Clinical Pharmacology & Therapeutics·2020· 42 citedOpen Access
The Exonuclease TREX1 Is in the SET Complex and Acts in Concert with NM23-H1 to Degrade DNA during Granzyme A-Mediated Cell Death
Molecular Cell·2006· 254 citedOpen Access
Erratum: siRNA-directed inhibition of HIV-1 infection
Nature Medicine·2003· 7 citedOpen Access
Tumor Suppressor NM23-H1 Is a Granzyme A-Activated DNase during CTL-Mediated Apoptosis, and the Nucleosome Assembly Protein SET Is Its Inhibitor
Cell·2003· 30 citedOpen Access
Tumor Suppressor NM23-H1 Is a Granzyme A-Activated DNase during CTL-Mediated Apoptosis, and the Nucleosome Assembly Protein SET Is Its Inhibitor
Cell·2003· 529 citedOpen Access
Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A
Nature Immunology·2003· 237 cited
siRNA-directed inhibition of HIV-1 infection
Nature Medicine·2002· 775 cited
HMG2 Interacts with the Nucleosome Assembly Protein SET and Is a Target of the Cytotoxic T-Lymphocyte Protease Granzyme A
Molecular and Cellular Biology·2002· 139 citedOpen Access
The Tumor Suppressor NM23-H1 Is the Granzyme A-Activated DNase and the Nucleosome Assembly Protein SET Is Its Inhibitor
Blood·2002
Granzyme A Activates an Endoplasmic Reticulum-associated Caspase-independent Nuclease to Induce Single-stranded DNA Nicks
Journal of Biological Chemistry·2001· 174 citedOpen Access
Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis
Proceedings of the National Academy of Sciences·2001· 165 citedOpen Access
Induction of Rapid Histone Degradation by the Cytotoxic T Lymphocyte Protease Granzyme A
Journal of Biological Chemistry·2001· 100 citedOpen Access
Granzyme A Loading Induces Rapid Cytolysis and a Novel Form of DNA Damage Independently of Caspase Activation
Immunity·1999· 227 citedOpen Access
A Role for Heat Shock Protein 27 in CTL-Mediated Cell Death
The Journal of Immunology·1998· 57 citedOpen Access
Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of them
Proceedings of the National Academy of Sciences·1997· 106 citedOpen Access
Characterization of hemolytic and cytotoxic Gallysins: A relationship with arylphorins
Developmental & Comparative Immunology·1997· 36 cited
Fitness and pregnancy: a round table discussion.
PubMed·1983· 1 cited

Frequent Co-authors

Judy Lieberman(13), Dong Zhang(7), Zusen Fan(5), Carl D. Novina(3), David Y. Oh(3), Arnold H. Greenberg(3), Michael F. Murray(2), Derek M. Dykxhoorn(2), Jonathan W. Riess(2), Sang‐Kyung Lee(2), Ronald G. Collman(2), Premlata Shankar(2), Phillip A. Sharp(2), Madhuri Jaju(2), Dipanjan Chowdhury(1), Pengcheng Zhu(1), Jung‐Suk Sung(1), Bruce Demple(1), Fred W. Perrino(1), Zhan Xu(1)