Patrick Aebischer

École Polytechnique Fédérale de Lausanne — Switzerland

Neuroscience · Life Sciences

102h-index30.1kcitations359works0.02yr avg
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Research Topics

Nerve injury and regeneration(125), Virus-based gene therapy research(42), Parkinson's Disease Mechanisms and Treatments(39), Neurogenesis and neuroplasticity mechanisms(39), Neurological disorders and treatments(39)

Publications359 total

Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults
Cell Reports Medicine·2022· 185 citedOpen Access
Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults
JAMA Network Open·2022· 152 citedOpen Access
Astrocyte‐targeting <scp>RNA</scp> interference against mutated superoxide dismutase 1 induces motoneuron plasticity and protects fast‐fatigable motor units in a mouse model of amyotrophic lateral sclerosis
Glia·2022· 14 citedOpen Access
Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population
European Journal of Clinical Nutrition·2021· 98 citedOpen Access
Expression of a miRNA targeting mutated SOD1 in astrocytes induces motoneuron plasticity and improves neuromuscular function in ALS mice
2021· 1 citedOpen Access
The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans
Nature Metabolism·2019· 489 citedOpen Access
TRANSLATING UROLITHIN A BENEFITS ON MUSCLE MITOCHONDRIA TO HUMANS
Innovation in Aging·2018· 2 citedOpen Access
Pour des universités de rang mondial
Futuribles·2018· 4 citedOpen Access
Evolution of the neurochemical profiles in the G93A-SOD1 mouse model of amyotrophic lateral sclerosis
Journal of Cerebral Blood Flow & Metabolism·2018· 20 citedOpen Access
Modulating the catalytic activity of AMPK has neuroprotective effects against α-synuclein toxicity
Molecular Neurodegeneration·2017· 44 citedOpen Access
An in vivo culture system for human embryos using an encapsulation technology: a pilot study
reroDoc Digital Library·2017· 11 cited
[P3–176]: F‐ACTIN NANO‐ARCHITECTURE IS COMPROMISED IN DENDRITIC SPINES OF PRIMARY NEURONS FROM APP/PS1 MICE AND IS RESTORED BY GLUTAREDOXIN‐1
Alzheimer s & Dementia·2017Open Access
ORALLY ADMINISTERED UROLITHIN A IS SAFE AND MODULATES MUSCLE AND MITOCHONDRIAL BIOMARKERS IN ELDERLY
Innovation in Aging·2017· 10 citedOpen Access
Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neuron<i>s</i>
Human Molecular Genetics·2016· 72 citedOpen Access
Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
Nature Medicine·2016· 984 citedOpen Access
Axonal Localization of Integrins in the CNS Is Neuronal Type and Age Dependent
eNeuro·2016· 47 citedOpen Access
De Lausanne à Yaoundé : l’aventure des MOOCs
Annales des Mines - Réalités industrielles·2016
606. Use of a Bicistronic Vector to Silence SOD1 in Motoneurons and Astrocytes for the Treatment of Familial Amyotrophic Lateral Sclerosis
Molecular Therapy·2016· 1 citedOpen Access
A subcutaneous cellular implant for passive immunization against amyloid-β reduces brain amyloid and tau pathologies
Brain·2016· 39 citedOpen Access
Spinal cord stimulation improves forelimb use in an alpha-synuclein animal model of Parkinson's disease
International Journal of Neuroscience·2016· 17 citedOpen Access
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Frequent Co-authors

Nicole Déglon(14), Bernard L. Schneider(11), Anne D. Zurn(7), Jocelyne Bloch(6), Yaping Chu(4), Didier Trono(4), Philippe Hantraye(4), Hilal A. Lashuel(4), Jacalyn McHugh(4), Clive N. Svendsen(4), Marina E. Emborg(3), Shuang Yang(3), Stéphane Palfi(3), Pénélope A. Andreux(3), Chris Rinsch(3), Johan Auwerx(3), Christophe Lo Bianco(3), William Blanco-Bose(3), Toufik Abbas‐Terki(3), Jolanta Szulc(3)