Nicole Déglon

University Hospital of Lausanne — Switzerland

Neuroscience · Life Sciences

70h-index15.1kcitations229works3.42yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Genetic Neurodegenerative Diseases(77), Virus-based gene therapy research(50), Mitochondrial Function and Pathology(48), Nerve injury and regeneration(35), CRISPR and Genetic Engineering(35)

Publications229 total

Selective striatal pathological changes in a novel human HTT exon 1 knock-in mouse model of Huntington's disease
Experimental Neurology·2025· 1 cited
Gene editing for Spinocerebellar ataxia type 3 taking advantage of the human ATXN3L paralog as replacement gene
Gene Therapy·2025Open Access
Extracellular PHF-tau modulates astrocyte mitochondrial dynamics and mediates neuronal connectivity
Translational Neurodegeneration·2025· 3 citedOpen Access
Plasminogen activator inhibitor-1 regulates Zika virus infection
2025Open Access
Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP/PS1 mice
Brain·2024· 13 citedOpen Access
Gene editing as a therapeutic strategy for spinocerebellar ataxia type-3
Revue Neurologique·2024· 3 citedOpen Access
Mono- and Biallelic Inactivation of Huntingtin Gene in Patient-Specific Induced Pluripotent Stem Cells Reveal HTT Roles in Striatal Development and Neuronal Functions
Journal of Huntington s Disease·2024· 4 citedOpen Access
Limitations of Dual-Single Guide RNA CRISPR Strategies for the Treatment of Central Nervous System Genetic Disorders
Human Gene Therapy·2023· 9 citedOpen Access
Importance of the lactate shuttle between astrocytes and neurons for brain activation
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2023
Semi-automated workflows to quantify AAV transduction in various brain areas and predict gene editing outcome for neurological disorders
Molecular Therapy — Methods & Clinical Development·2023· 6 citedOpen Access
Tau Transfer via Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System
Cells·2023· 25 citedOpen Access
Accumulation of Tau in Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System
2023· 2 citedOpen Access
Revisiting the outcome of adult wild-type <i>Htt</i> inactivation in the context of <i>HTT</i>-lowering strategies for Huntington’s disease
Brain Communications·2023· 5 citedOpen Access
Tau promotes oxidative stress-associated cycling neurons in S phase as a pro-survival mechanism: Possible implication for Alzheimer’s disease
Progress in Neurobiology·2022· 25 citedOpen Access
Disruption of Astrocyte-Dependent Dopamine Control in the Developing Medial Prefrontal Cortex Leads to Excessive Grooming in Mice
Biological Psychiatry·2022· 21 citedOpen Access
Central Nervous System Gene Therapy: Present Developments and Emerging Trends Accelerating Industry-Academia Pathways
Human Gene Therapy·2022· 2 citedOpen Access
Correction: Maximizing lentiviral vector gene transfer in the CNS
Gene Therapy·2022Open Access
Lactate transporters in the rat barrel cortex sustain whisker-dependent BOLD fMRI signal and behavioral performance
Proceedings of the National Academy of Sciences·2021· 41 citedOpen Access
Extracellular vesicles: Major actors of heterogeneity in tau spreading among human tauopathies
Molecular Therapy·2021· 42 citedOpen Access
Thrombolysis by PLAT/tPA increases serum free IGF1 leading to a decrease of deleterious autophagy following brain ischemia
Zenodo (CERN European Organization for Nuclear Research)·2021Open Access
page 1 of 12Next →

Frequent Co-authors

Patrick Aebischer(23), Philippe Hantraye(16), Emmanuel Brouillet(13), Gwennaëlle Aurégan(9), Noëlle Dufour(9), Luís Pereira de Almeida(9), Jocelyne Bloch(6), Anne D. Zurn(6), Gilles Bonvento(6), Raymonde Hässig(5), Stéphane Palfi(4), Martine Guillermier(4), Sandro Alves(4), Isabel Nascimento-Ferreira(4), Etienne Régulier(4), Marina E. Emborg(3), Shuang Yang(3), Yaping Chu(3), Myriam Schluep(3), Jean‐Marc Joseph(3)