Etienne Régulier

Roche (Switzerland) — Switzerland

Neuroscience · Life Sciences

23h-index2.4kcitations41works0.02yr avg
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Research Topics

Genetic Neurodegenerative Diseases(16), Mitochondrial Function and Pathology(13), Virus-based gene therapy research(11), Neurological disorders and treatments(7), Immunotherapy and Immune Responses(4)

Publications41 total

SMA - CLINICAL
Neuromuscular Disorders·2020
A Search for Systemic Manifestations of Spinal Muscular Atrophy (SMA): A Matched-Cohort Study Using Insurance Claims Data in the USA (1258)
Neurology·2020
PSY154 - ECONOMIC BURDEN OF BETA-THALASSEMIA: LITERATURE REVIEW
Value in Health·2018· 2 citedOpen Access
Participating Faculty: Characterizing Pulmonary Hypertension-Related Hospitalization Costs Among Medicare Advantage or Commercially Insured Patients With Pulmonary Arterial Hypertension: A Retrospective Database Study
The American Journal of Managed Care·2015
Characterizing pulmonary hypertension-related hospitalization costs among Medicare Advantage or commercially insured patients with pulmonary arterial hypertension: a retrospective database study.
PubMed·2015· 51 cited
Cost of a Pulmonary Arterial Hypertension-Related Hospitalization in Belgium
Value in Health·2014· 1 citedOpen Access
Hospitalization Costs Related To Pulmonary Hypertension (Ph) Among Medicare Advantage Or Commercially Insured Patients With Pulmonary Arterial Hypertension (Pah) In The United States
Value in Health·2013· 4 citedOpen Access
MAP Kinase Phosphatase 1 (MKP-1/DUSP1) Is Neuroprotective in Huntington's Disease via Additive Effects of JNK and p38 Inhibition
Journal of Neuroscience·2013· 111 citedOpen Access
Diminished hippocalcin expression in Huntington’s disease brain does not account for increased striatal neuron vulnerability as assessed in primary neurons
Journal of Neurochemistry·2009· 27 cited
Single-step detection of mutant huntingtin in animal and human tissues: A bioassay for Huntington’s disease
Analytical Biochemistry·2009· 127 cited
Dysregulation of Gene Expression in Primary Neuron Models of Huntington's Disease Shows That Polyglutamine-Related Effects on the Striatal Transcriptome May Not Be Dependent on Brain Circuitry
Journal of Neuroscience·2008· 94 citedOpen Access
Hsp104 antagonizes α-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease
Journal of Clinical Investigation·2008· 195 citedOpen Access
Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease
Human Molecular Genetics·2008· 93 citedOpen Access
Sensitive biochemical aggregate detection reveals aggregation onset before symptom development in cellular and murine models of Huntington’s disease
Journal of Neurochemistry·2007· 112 cited
Analysis of potential transcriptomic biomarkers for Huntington's disease in peripheral blood
Proceedings of the National Academy of Sciences·2007· 140 citedOpen Access
Haloperidol protects striatal neurons from dysfunction induced by mutated huntingtin in vivo
Neurobiology of Disease·2007· 59 citedOpen Access
Neuroprotection by Hsp104 and Hsp27 in Lentiviral-based Rat Models of Huntington's Disease
Molecular Therapy·2007· 136 citedOpen Access
Lentiviral-mediated expression of mutant ataxin-3 in the rat striatum induces neuropathological changes: A possible explanation for dystonia found in Machado-Joseph disease patients
Infoscience (Ecole Polytechnique Fédérale de Lausanne)·2007Open Access
CA150 Expression Delays Striatal Cell Death in Overexpression and Knock-In Conditions for Mutant Huntingtin Neurotoxicity
Journal of Neuroscience·2006· 53 citedOpen Access
Inhibition of Calcineurin by FK506 Protects against Polyglutamine-Huntingtin Toxicity through an Increase of Huntingtin Phosphorylation at S421
Journal of Neuroscience·2006· 134 citedOpen Access
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Frequent Co-authors

Nicole Déglon(15), Patrick Aebischer(12), Ruth Luthi‐Carter(6), Emmanuel Brouillet(6), Stéphane Paul(6), Yves Poitevin(5), Majid Mehtali(4), Valérie Perrin(4), Diana Zala(4), Elke Hunsche(4), Raymonde Hässig(3), Luís Pereira de Almeida(3), Yves Beuzard(3), Paul Buzinec(3), Horst E. Homann(3), Philippe Erbs(2), Jacqueline Kintz(2), Emilie Colin(2), Sandrine Humbert(2), Frédéric Saudou(2)