Tinoush Moulaei

Eloxx Pharmaceuticals (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index546citations23works0.02yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(9), Advanced biosensing and bioanalysis techniques(4), RNA and protein synthesis mechanisms(4), HIV Research and Treatment(3), Glycosylation and Glycoproteins Research(3)

Publications23 total

Monkeypox Virus Clade IIb Isolate Exhibits Reduced Virulence Relative to Clade IIa Isolates in Multiple Murine Models
2025
Recombinant chimeric horsepox virus (TNX-801) is attenuated relative to vaccinia virus strains in both <i>in vitro</i> and <i>in vivo</i> models
mSphere·2024Open Access
Recombinant chimeric Horsepox Virus (TNX-801) is attenuated relative to Vaccinia Virus Strains in Human Primary Cell Lines and in Immunocompromised Mice
2023Open Access
Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus
Retrovirology·2015· 40 citedOpen Access
B-DNA structure is intrinsically polymorphic: even at the level of base pair positions
Nucleic Acids Research·2011· 55 citedOpen Access
Erratum: Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1
Nature Structural & Molecular Biology·2011· 1 citedOpen Access
Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity
Structure·2010· 93 citedOpen Access
The phosphate clamp: a small and independent motif for nucleic acid backbone recognition
Nucleic Acids Research·2010· 60 citedOpen Access
Topology of the disulfide bonds in the antiviral lectin scytovirin
Protein Science·2010· 19 citedOpen Access
Monomeric Griffithsin with two Gly-Ser Insertions
2010
Monomeric Griffithsin in Complex with a High-Mannose Branched Carbohydrate
2010
Monomeric Griffithsin with a Single Gly-Ser Insertion
2010
Application of Anomalous Diffraction Methods to the Study of DNA and DNA-Complexes
Methods in molecular biology·2009· 3 cited
Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1
Nature Structural & Molecular Biology·2009· 3 citedOpen Access
Structure of human Plk1-PBD in complex with PLHSpT
2009
Locating monovalent cations in one turn of G/C rich B-DNA
2009
Crystal structure of one turn of G/C rich B-DNA revisited
2009
Atomic‐resolution crystal structure of the antiviral lectin scytovirin
Protein Science·2007· 37 citedOpen Access
A Third Mode of DNA Binding:  Phosphate Clamps by a Polynuclear Platinum Complex
Journal of the American Chemical Society·2006· 174 cited
A Backbone binding DNA complex
2006
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Frequent Co-authors

Alexander Wlodawer(9), Seiji Komeda(7), Loren Dean Williams(5), Kristen Kruger Woods(4), Shilpa R. Shenoy(4), James B. McMahon(4), Barry R. O’Keefe(4), Tatsuya Maehigashi(4), N.E. Ziolkowska(4), Masahiko Chikuma(3), L.D. Williams(3), Stephanie V. Trefry(3), Christy N Raney(3), Amy L Cregger(3), Chase A Gonzales(3), Robert N Enamorado(3), Nelson A Martinez(3), Deborah S Gohegan(3), Sina Bavari(3), Nicholas P. Farrell(2)