Olivera Grubisha

Eli Lilly (United States) — United States

Neuroscience · Life Sciences

13h-index761citations21works0.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(4), Plant Virus Research Studies(3), Poxvirus research and outbreaks(3), Alzheimer's disease research and treatments(2), Ubiquitin and proteasome pathways(2)

Publications21 total

Comparative Analysis of Small-Molecule LIMK1/2 Inhibitors: Chemical Synthesis, Biochemistry, and Cellular Activity
Journal of Medicinal Chemistry·2022· 19 citedOpen Access
Metabotropic Glutamate Receptors Modulate Exocytotic Tau Release and Propagation
Journal of Pharmacology and Experimental Therapeutics·2022· 11 citedOpen Access
A toolkit for the identification of NEAT1_2/paraspeckle modulators
Nucleic Acids Research·2022· 15 citedOpen Access
Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase
Communications Biology·2022· 6 citedOpen Access
Tyrosine 121 moves revealing a druggable pocket that couples catalysis to ATP-binding in serine racemase
2021Open Access
[O1–07–05]: REGULATED RELEASE OF HYPER‐PHOSPHORYLATED, AGGREGATED AND SEEDING COMPETENT TAU FROM RODENT BRAINS AND HUMAN SYNAPTOSOMES
Alzheimer s & Dementia·2017
[P3–081]: ESTABLISHING MICROFLUIDIC DEVICES AS AN <i>IN VITRO</i> NEURONAL MODEL FOR STUDYING MOLECULAR AND FUNCTIONAL ASPECTS OF TRANSNEURONAL TAU PROPAGATION
Alzheimer s & Dementia·2017Open Access
Phosphodiesterase-1b (Pde1b) knockout mice are resistant to forced swim and tail suspension induced immobility and show upregulation of Pde10a
Psychopharmacology·2017· 25 cited
Gain and Loss of Function of P2X<sub>7</sub> Receptors: Mechanisms, Pharmacology and Relevance to Diabetic Neuropathic Pain
Molecular Pain·2014· 78 citedOpen Access
Pharmacological profiling of the <scp>TRPV3</scp> channel in recombinant and native assays
British Journal of Pharmacology·2013· 21 citedOpen Access
Pharmacological profiling of native group II metabotropic glutamate receptors in primary cortical neuronal cultures using a FLIPR
Neuropharmacology·2012· 30 cited
DARPin-Assisted Crystallography of the CC2-LZ Domain of NEMO Reveals a Coupling between Dimerization and Ubiquitin Binding
Journal of Molecular Biology·2009· 38 cited
Regulation of innate immunity and inflammation by the mitotic kinase PLK1 through inhibition of IKKε activity
Cytokine·2009
Obtention de mutants de la protéine NEMO par mutagenèse dirigée afin de valider la structure au rayon X et obtention de peptides inhibiteurs de l'activation de la voie NF-kB
HAL (Le Centre pour la Communication Scientifique Directe)·2009
The Zinc Finger of NEMO Is a Functional Ubiquitin-binding Domain
Journal of Biological Chemistry·2008· 84 citedOpen Access
Modèle structural du domaine CC2-LZ en association avec de l'ubiquitine
HAL (Le Centre pour la Communication Scientifique Directe)·2008
Metabolite of SIR2 Reaction Modulates TRPM2 Ion Channel
Journal of Biological Chemistry·2006· 151 citedOpen Access
Small molecule regulation of Sir2 protein deacetylases
FEBS Journal·2005· 128 cited
Genetic Analysis of the Vaccinia Virus I6 Telomere-Binding Protein Uncovers a Key Role in Genome Encapsidation
Journal of Virology·2003· 47 citedOpen Access
Clustered Charge-to-Alanine Mutagenesis of the Vaccinia Virus A20 Gene: Temperature-Sensitive Mutants Have a DNA-Minus Phenotype and Are Defective in the Production of Processive DNA Polymerase Activity
Journal of Virology·2001· 39 citedOpen Access
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Frequent Co-authors

Daniel Ursu(5), Helen Sanger(5), Florence Cordier(4), Michel Véron(4), Fabrice Agou(4), Emanuele Sher(4), Lisa M. Broad(4), Jason A. Gillespie(4), John Atack(4), Paula Traktman(3), M. Kamińska(3), S. Duquerroy(3), Élisabeth Fontan(3), Jeanne Chiaravalli(3), James A. Monn(3), Simon E. Ward(3), Karen T Elvers(3), Michael Hutton(3), Suchira Bose(3), John M. Denu(2)