Kelli L. VanDussen

Cincinnati Children's Hospital Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index3.7kcitations92works0.72yr avg
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Research Topics

Inflammatory Bowel Disease(28), Cancer Cells and Metastasis(17), Digestive system and related health(16), Microscopic Colitis(13), Helicobacter pylori-related gastroenterology studies(11)

Publications92 total

Supplementation with endogenous healthy gut metabolites reverses the disruptions of in vitro and ex vivo epithelial functions induced by fecal content from IBD patients
Gut Microbes·2025Open Access
Short Ileal Microvillus Length Phenotype Associates with Progression from Inflammatory to Complicated Disease Behavior in Pediatric Crohn’s Disease
Inflammatory Bowel Diseases·2025· 1 citedOpen Access
Sa1783: FECAL CONTENT FROM IBD PATIENTS CAUSES MORE SEVERE EPITHELIAL DAMAGE THAN FECAL CONTENT FROM HEALTHY DONORS, WHICH CAN BE MODERATED BY SUPPLEMENTATION OF METABOLITES COCKTAIL
Gastroenterology·2025
22: DEVELOPMENT OF A PATIENT-DERIVED AIR-LIQUID INTERFACE MODEL TO INVESTIGATE STRUCTURAL DISRUPTIONS IN THE ENTEROCYTE TERMINAL WEB IN PEDIATRIC CROHN’S DISEASE PATIENTS
Gastroenterology·2025
Su1989: NOVEL HYBRID-AI ANALYSIS OF ILEAL TRANSCRIPTOME FROM MULTIPLE CROHN’S DISEASE COHORTS IDENTIFIES UNIQUE MOLECULAR PATHWAY CLUSTERS THAT PREDICT OUTCOME
Gastroenterology·2025
277: TRANSGENIC PPARA OVEREXPRESSION IN INTESTINAL EPITHELIAL CELLS RAPIDLY REMODELS CRYPT HOMEOSTASIS
Gastroenterology·2025
P0207 Ex-vivo colonoids derived from ulcerative colitis patients retain epithelial inflammatory “memory” even after several passages, which may contribute to UC chronicity
Journal of Crohn s and Colitis·2025
DOP124 Fecal content from IBD patients causes more severe epithelial damage than fecal content from healthy donors, which can be moderated by supplementation of metabolites cocktail
Journal of Crohn s and Colitis·2025
The Homeobox Transcription Factor CUX1 Coordinates Postnatal Epithelial Developmental Timing but Is Dispensable for Lung Organogenesis and Regeneration
American Journal of Respiratory Cell and Molecular Biology·2024· 4 citedOpen Access
Ileal Paneth Cell Phenotype is a Cellular Biomarker for Pouch Complications in Ulcerative Colitis
Journal of Crohn s and Colitis·2024· 5 citedOpen Access
Tu1722 THE ENTEROCYTE TERMINAL WEB STRUCTURE IS DISRUPTED IN NON-INFLAMED ILEAL TISSUE OF PEDIATRIC CROHN'S DISEASE PATIENTS
Gastroenterology·2024
916 PRO-FIBROTIC DUOX2 GENE VARIANTS IMPAIR CELL METABOLISM AND INCREASE TISSUE COLLAGEN CONTENT IN AN INDUCED PLURIPOTENT STEM CELL DERIVED HUMAN INTESTINAL ORGANOID MODEL OF ILEAL CROHN'S DISEASE
Gastroenterology·2024
37 SINGLE-CELL-RESOLVED CHROMATIN ACCESSIBLITY MAPS OF INFLAMMATORY BOWEL DISEASE INTESTINE NOMINATE CELL TYPES AND CONTEXTS MEDIATING GENETIC DISEASE RISK
Gastroenterology·2024
Sa1869 FECAL CONTENT FROM IBD PATIENTS DISTURBS EPITHELIAL FUNCTIONS IN TWO MODEL SYSTEMS
Gastroenterology·2024
110 IN VITRO MODELING OF INTESTINAL BRUSH BORDER MATURATION USING ORGANOID-DERIVED INTESTINAL EPITHELIAL CELLS AND THE AIR-LIQUID INTERFACE
Gastroenterology·2024
Tu1720 SHORT ILEAL MICROVILLUS LENGTH PREDICTS STRICTURING DISEASE BEHAVIOR AND BOWEL RESECTION SURGERY IN PEDIATRIC CROHN'S DISEASE
Gastroenterology·2024
The homeobox transcription factor Cux1 coordinates postnatal epithelial developmental timing but is dispensable for lung organogenesis and regeneration
2024Open Access
Accessible chromatin maps of inflammatory bowel disease intestine nominate cell-type mediators of genetic disease risk
2024· 4 citedOpen Access
P118 Fecal content from IBD patients disturbs epithelial functions in two model systems
Journal of Crohn s and Colitis·2024Open Access
Microbiota-produced indole metabolites disrupt mitochondrial function and inhibit Cryptosporidium parvum growth
Cell Reports·2023· 42 citedOpen Access
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Frequent Co-authors

Thaddeus S. Stappenbeck(28), Ta‐Chiang Liu(14), Linda C. Samuelson(10), Matthew A. Ciorba(8), L. David Sibley(7), Dermot McGovern(7), Lee A. Denson(7), Shanshan Xiong(6), Lisa J. Funkhouser-Jones(6), Talin Haritunians(6), Peter J. Dempsey(5), Brian D. Muegge(5), Georgia Wilke(5), Megan T. Baldridge(5), Tzipi Braun(5), Yi Wang(4), Chin‐Wen Lai(4), Dalin Li(4), Katherine Li(4), Jacqueline Perrigoue(4)