Brian D. Muegge

Washington University in St. Louis — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

27h-index42.4kcitations44works2.82yr avg
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Research Topics

Gut microbiota and health(9), Inflammatory Bowel Disease(5), Advanced Condensed Matter Physics(5), Advanced biosensing and bioanalysis techniques(4), Multiferroics and related materials(4)

Publications44 total

Endogenous fungi regulate host lipid metabolism to promote intestinal wound repair 2968
The Journal of Immunology·2025Open Access
SMURF: soft-segmentation for single-cell reconstruction and topological analysis of spatial transcriptomic data
2025· 1 citedOpen Access
EGR1 drives sex-differences in glioblastoma tumorigenicity
2025· 1 citedOpen Access
Mild Duodenal Mucosal Injury and Increased Type I Interferon Signaling Are Preludes to Celiac Disease
Laboratory Investigation·2025· 2 citedOpen Access
NAD <sup>+</sup> precursors and bile acid sequestration treat preclinical refractory environmental enteric dysfunction
Science Translational Medicine·2024· 10 citedOpen Access
Islet primary cilia motility controls insulin secretion
Science Advances·2022· 57 citedOpen Access
Mesothelium-Derived Factors Shape GATA6-Positive Large Cavity Macrophages
The Journal of Immunology·2022· 10 citedOpen Access
963: HIGH FAT DIET-INDUCED MICROVILLUS SHORTENING OF ILEAL ENTEROCYTES IS RESCUED BY ACTIVATION OF PPARα SIGNALING IN MICE
Gastroenterology·2022
1152: REVERSE TRANSLATION APPROACH REVEALS POTENTIAL THERAPEUTIC TARGETS FOR ENVIRONMENTAL ENTERIC DYSFUNCTION
Gastroenterology·2022
Islet primary cilia motility controls insulin secretion
2021· 5 citedOpen Access
Biofilm Formation and Virulence of Shigella flexneri Are Modulated by pH of Gastrointestinal Tract
Infection and Immunity·2021· 19 citedOpen Access
Reverse translation approach generates a signature of penetrating fibrosis in Crohn’s disease that is associated with anti-TNF response
Gut·2021· 29 cited
<i>Debaryomyces</i> is enriched in Crohn’s disease intestinal tissue and impairs healing in mice
Science·2021· 209 citedOpen Access
Biofilm Formation and Virulence of <i>Shigella flexneri</i> is Modulated by pH of Gastrointestinal Tract
2020· 1 cited
769 DIETARY PROTEIN DIFICIENCY RECAPITULATES KEY HISTOLOGIC AND TRANSCRIPTOMIC CHANGES OF ENVIRONMENTAL ENTERIC DYSFUNCTION
Gastroenterology·2020
Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells
Cell·2019· 199 citedOpen Access
Sa1895 – Characterization and Modeling of the Creeping Fat that Occurs in Crohn’s Disease
Gastroenterology·2019· 1 cited
PAI-1 augments mucosal damage in colitis
Science Translational Medicine·2019· 67 citedOpen Access
Temporal Regulation of the Bacterial Metabolite Deoxycholate during Colonic Repair Is Critical for Crypt Regeneration
Cell Host & Microbe·2018· 61 citedOpen Access
Abnormal Small Intestinal Epithelial Microvilli in Patients With Crohn's Disease
Gastroenterology·2018· 113 cited
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Frequent Co-authors

Ta‐Chiang Liu(11), Thaddeus S. Stappenbeck(11), Jeffrey I. Gordon(10), Umang Jain(8), Shanshan Xiong(7), Chin‐Wen Lai(7), Mark Richter(6), Rob Knight(5), Qiuhe Lu(5), Kelli L. VanDussen(5), Dan Knights(4), Tanya Yatsunenko(4), I-Ling Chiang(4), G. C. Lau(4), E. L. Duncan(4), R. J. Cava(4), Justin Kuczynski(3), Elizabeth K. Costello(3), Catherine Lozupone(3), Bernard Henrissat(3)