Adam W. Mailloux

University of Iowa — United States

Immunology and Microbiology · Life Sciences

19h-index1.3kcitations76works1.02yr avg
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Research Topics

Immune Cell Function and Interaction(26), Acute Myeloid Leukemia Research(15), Immunotherapy and Immune Responses(13), T-cell and B-cell Immunology(11), Chronic Lymphocytic Leukemia Research(10)

Publications75 total

Hypoxic stress granules trigger immunogenic dormancy in lung cancer
2026Open Access
Hypoxia induces a state of immunogenic dormancy in non-small cell lung cancer by blocking protein translation of the MHC class I pathway associated with m5C hypermethylation of mRNA 3663
The Journal of Immunology·2025Open Access
Abstract 7249: TME hypoxia drives immunopeptidomic deficiencies in non-small cell lung cancer by blocking translation of interferon stimulated genes within the MHC I pathway
Cancer Research·2025· 1 cited
Abstract 7250: Extracellular acidity in the TME interferes with the IFN-γ induction of the immunoproteasome
Cancer Research·2025· 1 cited
Potentiating the effect of immunotherapy in pancreatic cancer using gas-entrapping materials
Biomaterials·2025· 2 cited
Hypoxia-mediated repression of pyruvate carboxylase drives immunosuppression
UNC Libraries·2024Open Access
Hypoxia-mediated repression of pyruvate carboxylase drives immunosuppression
Breast Cancer Research·2024· 3 citedOpen Access
Data from STING Signaling in Melanoma Cells Shapes Antigenicity and Can Promote Antitumor T-cell Activity
2023Open Access
Data from STING Signaling in Melanoma Cells Shapes Antigenicity and Can Promote Antitumor T-cell Activity
2023Open Access
Abstract 2994: Hypoxia blocks the presentation of tumor antigens to CD8+ T cells
Cancer Research·2023· 1 cited
Supplementary Data (for Review only) from STING Signaling in Melanoma Cells Shapes Antigenicity and Can Promote Antitumor T-cell Activity
2023Open Access
Supplementary Data (for Review only) from STING Signaling in Melanoma Cells Shapes Antigenicity and Can Promote Antitumor T-cell Activity
2023Open Access
Abstract 2997: Tumor hypoxia blocks the induction of antigen processing machinery
Cancer Research·2023
Low‐Cost, High‐Pressure‐Synthesized Oxygen‐Entrapping Materials to Improve Treatment of Solid Tumors
Advanced Science·2023· 18 citedOpen Access
Checkpoint blockade accelerates a novel switch from an NKT-driven TNFα response toward a T cell driven IFN-γ response within the tumor microenvironment
Journal for ImmunoTherapy of Cancer·2021· 4 citedOpen Access
Correction: <i>Systemic pro-inflammatory response identifies patients with cancer with adverse outcomes from SARS-CoV-2 infection: the OnCovid Inflammatory Score</i>
Journal for ImmunoTherapy of Cancer·2021· 4 citedOpen Access
Inducible Tertiary Lymphoid Structures: Promise and Challenges for Translating a New Class of Immunotherapy
Frontiers in Immunology·2021· 39 citedOpen Access
Large Scale <i>Ex Vivo</i> Expansion of Γδ T Cells Using Artificial Antigen Presenting Cells for the Treatment of Acute Myeloid Leukemia
Blood·2020
226 Checkpoint blockade hastens a switch from an NKT dominant, TNF-alpha-driven to a CD4+/CD8+ IFN-gamma-driven immune response within MC-38 tumor-infiltrating lymphocytes
Regular and Young Investigator Award Abstracts·2020· 3 citedOpen Access
High-Dimensional Flow Cytometry Analysis of Regulatory Receptors on Human T Cells, NK Cells, and NKT Cells
Methods in molecular biology·2020· 3 citedOpen Access
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Frequent Co-authors

Pearlie K. Epling‐Burnette(22), Alan F. List(13), James J. Mulé(12), Rami S. Komrokji(11), Eric Padron(9), Jessica M. McDaniel(7), Thomas P. Loughran(6), Ryosuke Nakagawa(6), Jeffrey S. Painter(5), Jeffrey E. Lancet(5), Satoshi Nemoto(5), Ying Han(5), Matthew G. Smith(5), Heena Panchal(5), Kathy L. McGraw(4), Matthew R. Young(4), Patricio Perez-Villarroel(4), Genyuan Zhu(4), Jaroslaw P. Maciejewski(4), Ronald Paquette(4)