Shao‐En Ong

University of Washington — United States

Chemistry · Physical Sciences

40h-index19.1kcitations136works7.52yr avg
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Research Topics

Advanced Proteomics Techniques and Applications(37), Mass Spectrometry Techniques and Applications(23), Ubiquitin and proteasome pathways(16), RNA modifications and cancer(14), Protein Kinase Regulation and GTPase Signaling(12)

Publications135 total

DDEL-10. Mild inhibition of microtubule assembly disrupts mitochondria function in glioblastoma in interphase via Drp1 activation
Neuro-Oncology·2025Open Access
<i>Plasmodium falciparum</i> exploits NUAK1 to establish infection in human erythrocytes
2025Open Access
diaPASEF-Powered Chemoproteomics Enables Deep Kinome Interaction Profiling
Journal of Proteome Research·2025· 1 citedOpen Access
Mitochondrial calcium signaling regulates branched-chain amino acid catabolism in fibrolamellar carcinoma
Science Advances·2025· 2 citedOpen Access
<i>Xist</i> Repeat A coordinates an assembly of SR proteins to recruit SPEN and induce gene silencing
2025· 4 citedOpen Access
AKAP2 Is a Triple Negative Breast Cancer Signaling Scaffold and Potentiates Tumor Growth In Vivo (Abstract ID: 169170)
Journal of Pharmacology and Experimental Therapeutics·2025
Cellular RNA interacts with MAVS to promote antiviral signaling
Science·2024· 27 citedOpen Access
diaPASEF-Powered Chemoproteomics Enables Deep Kinome Interaction Profiling
2024· 2 citedOpen Access
Nascent transcript O-MAP reveals the molecular architecture of a single-locus subnuclear compartment built by RBM20 and the <i>TTN</i> RNA
2024· 5 citedOpen Access
Investigating a Novel Erythrocyte Kinase and Its Impact on <i>Plasmodium Falciparum</i> Infection
Blood·2024Open Access
Multiomic characterization of RNA microenvironments by oligonucleotide-mediated proximity-interactome mapping
Nature Methods·2024· 29 citedOpen Access
Single-cell sensor analyses reveal signaling programs enabling Ras-G12C drug resistance
Nature Chemical Biology·2024· 6 citedOpen Access
Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma
2024· 1 citedOpen Access
Abstract 1663: Single-cell signaling analysis reveals that major vault protein facilitates RasG12C inhibitor resistance
Cancer Research·2024
Discovery of a Cushing’s syndrome protein kinase A mutant that biases signaling through type I AKAPs
Science Advances·2024· 10 citedOpen Access
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
Nature Biotechnology·2024· 27 citedOpen Access
Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma
Cell Reports·2024· 14 citedOpen Access
Single-cell signaling analysis reveals that Major Vault Protein facilitates RasG12C inhibitor resistance
2023· 2 citedOpen Access
Cellular RNA Interacts with MAVS to Promote Antiviral Signaling
2023· 2 citedOpen Access
Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma
2023Open Access
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Frequent Co-authors

Matthias Mann(12), Steven A. Carr(11), Martin Golkowski(9), Anthony K. L. Leung(8), Ho-Tak Lau(7), Blagoy Blagoev(5), Irina Kratchmarova(4), Stuart L. Schreiber(4), F. Donelson Smith(4), John D. Scott(4), Akhilesh Pandey(3), Vamsi K. Mootha(3), Monica Schenone(3), Michael B. Yaffe(3), Marcel A.T.M. van Vugt(3), Robert Lyle McPherson(3), Teck Keong Seow(3), Rosa C. M. Y. Liang(3), Keli Ou(3), Casey M. Daniels(3)