Anthony K. L. Leung

Johns Hopkins University — United States

Medicine · Health Sciences

47h-index9.9kcitations148works4.02yr avg
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Research Topics

PARP inhibition in cancer therapy(72), RNA Research and Splicing(35), Calcium signaling and nucleotide metabolism(27), RNA modifications and cancer(24), Toxin Mechanisms and Immunotoxins(23)

Publications148 total

Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection
Nature Communications·2025· 2 citedOpen Access
Author Correction: Evidence for improved DNA repair in the long-lived bowhead whale
Nature·2025Open Access
Evidence for improved DNA repair in the long-lived bowhead whale
Nature·2025· 12 citedOpen Access
Nuclear poly(A)-binding protein and nucleolin utilize their RNA recognition motifs to read PAR chains
Nucleic Acids Research·2025· 1 citedOpen Access
PARP10 is critical for stress granule initiation
Life Science Alliance·2025· 4 citedOpen Access
Transient Poly(ADP-Ribose) Triggers FUS Condensation Hysteresis via a Prion-Like Mechanism
2025· 1 citedOpen Access
Crosstalk between iron and flavins in the opportunistic fungal pathogen Candida albicans
Journal of Biological Chemistry·2025Open Access
Insulin post-transcriptional regulation via PARP12-mediated ADP- ribosylation
2025Open Access
Proteogenomic reprogramming to a functional human blastomere-like stem cell state via a PARP-DUX4 regulatory axis
Cell Reports·2025· 1 citedOpen Access
Interferon-induced PARP14-mediated ADP-ribosylation in p62 bodies requires the ubiquitin-proteasome system
The EMBO Journal·2025· 9 citedOpen Access
dELTA-MS: A Mass Spectrometry-Based Proteomics Approach for Identifying ADP-Ribosylation Sites and Forms
Journal of Proteome Research·2025Open Access
PARPs and ADP-ribosylation-mediated biomolecular condensates: determinants, dynamics, and disease implications
Trends in Biochemical Sciences·2025· 9 citedOpen Access
Regulation of stress granule maturation and dynamics by poly(ADP-ribose) interaction with PARP13
Nature Communications·2025· 5 citedOpen Access
Flap endonuclease 1 repairs DNA-protein cross-links via ADP-ribosylation–dependent mechanisms
Science Advances·2025· 7 citedOpen Access
PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation
EMBO Reports·2024· 22 citedOpen Access
Author Correction: Cation-induced intramolecular coil-to-globule transition in poly(ADP-ribose)
Nature Communications·2024Open Access
Poly ADP-ribose signaling is dysregulated in Huntington disease
Proceedings of the National Academy of Sciences·2024· 13 citedOpen Access
Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection
2024· 4 citedOpen Access
Cation-induced intramolecular coil-to-globule transition in poly(ADP-ribose)
Nature Communications·2024· 7 citedOpen Access
Decreasing ZAP Poly(ADP-ribose) Binding Enhances Antiviral Activity Against Alphaviruses
2024Open Access
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Frequent Co-authors

Shao‐En Ong(8), Angus I. Lamond(8), Phillip A. Sharp(7), Robert Lyle McPherson(7), Morgan Dasovich(6), Diane E. Griffin(5), Jens Andersen(4), Yun Wah Lam(4), Carol E. Lyon(4), Matthias Mann(4), Casey M. Daniels(4), Rachy Abraham(4), Christina A. Vivelo(4), Paul Chang(3), Dmitri V. Filippov(3), Mohsen Badiee(3), Archa H. Fox(2), Ivan Ahel(2), Michael S. Cohen(2), Anthony R. Fehr(2)