Anthony R. Fehr

University of Kansas — United States

Medicine · Health Sciences

34h-index10.6kcitations81works5.62yr avg
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Research Topics

SARS-CoV-2 and COVID-19 Research(43), PARP inhibition in cancer therapy(29), interferon and immune responses(11), Viral gastroenteritis research and epidemiology(10), Animal Virus Infections Studies(10)

Publications81 total

SARS-CoV-2 and MERS-CoV disrupt host protein synthesis via nsp1 with differential effects on the integrated stress response
2025Open Access
The autoimmunity-associated minor allele of PTPN22 enhances innate antiviral immunity during coronavirus infection 3695
The Journal of Immunology·2025Open Access
PARP14 is an interferon-induced host factor that promotes IFN production and affects the replication of multiple viruses
mBio·2025· 2 citedOpen Access
Quorum sensing regulation by the nitrogen phosphotransferase system in <i>Pseudomonas aeruginosa</i>
Journal of Bacteriology·2025· 1 citedOpen Access
Mutations differentially affecting the coronavirus Mac1 ADP-ribose binding and hydrolysis activities indicate that it promotes multiple stages of the viral replication cycle
Journal of Virology·2025· 1 citedOpen Access
An Autoimmunity-associated allele of <i>PTPN22</i> enhances innate antiviral immunity to protect against acute coronavirus infection
2025Open Access
IFN-γ signaling is required for the efficient replication of murine hepatitis virus (MHV) strain JHM in the brains of infected mice
PLoS ONE·2025Open Access
Identification of a series of pyrrolo-pyrimidine-based SARS-CoV-2 Mac1 inhibitors that repress coronavirus replication
mBio·2025· 4 citedOpen Access
Mutations differentially affecting the coronavirus Mac1 ADP-ribose binding and hydrolysis activities indicate that it promotes multiple stages of the viral replication cycle
2025Open Access
Quorum sensing regulation by the nitrogen phosphotransferase system in <i>Pseudomonas aeruginosa</i>
2025· 1 citedOpen Access
IFN- <i>γ</i> signaling is required for the efficient replication of murine hepatitis virus (MHV) strain JHM in the brains of infected mice
2025Open Access
Identification of a series of pyrrolo-pyrimidine based SARS-CoV-2 Mac1 inhibitors that repress coronavirus replication
2024· 1 citedOpen Access
Mutation of a highly conserved isoleucine residue in loop 2 of several β-coronavirus macrodomains indicates that enhanced ADP-ribose binding is detrimental for replication
Journal of Virology·2024· 8 citedOpen Access
The Autoimmunity-Associated Minor Allele of PTPN22 Enhances Antiviral Immunity During Coronavirus Infection
The Journal of Immunology·2024
PARP14 is an interferon (IFN)-induced host factor that promotes IFN production and affects the replication of multiple viruses
2024· 15 citedOpen Access
Discovery of 2-Amide-3-methylester Thiophenes that Target SARS-CoV-2 Mac1 and Repress Coronavirus Replication, Validating Mac1 as an Antiviral Target
Journal of Medicinal Chemistry·2024· 17 citedOpen Access
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling
Proceedings of the National Academy of Sciences·2024· 41 citedOpen Access
Mutation of a highly conserved isoleucine residue in loop 2 of several 𝛽-coronavirus macrodomains indicates that enhanced ADP-ribose binding is detrimental to infection
2024· 8 citedOpen Access
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling
2023· 12 citedOpen Access
An Update on the Current State of SARS-CoV-2 Mac1 Inhibitors
Pathogens·2023· 16 citedOpen Access
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Frequent Co-authors

Stanley Perlman(20), Rudragouda Channappanavar(10), Yousef M. Alhammad(10), Dong Yü(8), Jessica J. Pfannenstiel(8), David K. Meyerholz(6), Jeremiah Athmer(6), Catherine M. Kerr(6), Matthew Grunewald(6), David K. Johnson(6), Joseph J. O’Connor(6), Dana Ferraris(5), L. Lehtiö(4), Anthony K. L. Leung(4), Anuradha Roy(4), Peter R. McDonald(4), Sunil More(4), Rahul Vijay(3), Jincun Zhao(3), Ivan Ahel(3)