Miriam Sciaccaluga

University of Perugia — Italy

Neuroscience · Life Sciences

20h-index1.2kcitations50works4.82yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(18), Receptor Mechanisms and Signaling(10), Ion channel regulation and function(9), Nicotinic Acetylcholine Receptors Study(7), Parkinson's Disease Mechanisms and Treatments(5)

Publications50 total

Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease
Epilepsia·2025Open Access
Advances in gene therapy for Lafora disease: Intravenous recombinant adeno‐associated virus‐mediated delivery of <i>EPM2A</i> and <i>EPM2B</i> genes
Clinical and Translational Medicine·2025· 1 citedOpen Access
Etiological diagnosis of late‐onset epilepsy: A key priority for Italian epileptologists – Insights from a LICE survey
Epilepsia Open·2025Open Access
Oligomeric alpha-synuclein causes early synaptic dysfunction of the corticostriatal pathway associated with non-motor symptoms
npj Parkinson s Disease·2025· 5 citedOpen Access
Neuronal Hyperexcitability: A Key to Unravelling Hippocampal Synaptic Dysfunctions in Lafora Disease
2025Open Access
Evaluating bexicaserin for the treatment of developmental epileptic encephalopathies
Expert Opinion on Pharmacotherapy·2024· 16 cited
Gene therapy for Lafora disease in the Epm2a mouse model
Molecular Therapy·2024· 12 citedOpen Access
Cannabidiol: metabolism and clinical efficacy in epileptic patients
Expert Opinion on Drug Metabolism & Toxicology·2024· 5 cited
Locally Synthetized 17-β-Estradiol Reverses Amyloid-β-42-Induced Hippocampal Long-Term Potentiation Deficits
International Journal of Molecular Sciences·2024· 4 citedOpen Access
Traditional and Innovative Anti-seizure Medications Targeting Key PhysiopathologicalMechanisms: Focus on Neurodevelopment and Neurodegeneration
Current Neuropharmacology·2023· 6 citedOpen Access
Epm2aR240X knock-in mice present earlier cognitive decline and more epileptic activity than Epm2a mice
Neurobiology of Disease·2023· 7 citedOpen Access
Non-competitive AMPA glutamate receptors antagonism by perampanel as a strategy to counteract hippocampal hyper-excitability and cognitive deficits in cerebral amyloidosis
Neuropharmacology·2022· 16 cited
A positive allosteric modulator of mGlu4 receptors restores striatal plasticity in an animal model of l-Dopa-induced dyskinesia
Neuropharmacology·2022· 7 cited
Interleukin-17 affects synaptic plasticity and cognition in an experimental model of multiple sclerosis
Cell Reports·2021· 81 citedOpen Access
Interleukin-17 axis in the modulation of cortical and subcortical synaptic plasticity across disease stages in experimental multiple sclerosis
Journal of the Neurological Sciences·2021
Dopamine-dependent early synaptic and motor dysfunctions induced by α-synuclein in the nigrostriatal circuit
Brain·2021· 116 citedOpen Access
M2 Muscarinic Receptor Activation Impairs Mitotic Progression and Bipolar Mitotic Spindle Formation in Human Glioblastoma Cell Lines
Cells·2021· 8 citedOpen Access
An Unbalanced Synaptic Transmission: Cause or Consequence of the Amyloid Oligomers Neurotoxicity?
International Journal of Molecular Sciences·2021· 68 citedOpen Access
Developmental impaired Akt signaling in the Shank1 and Shank3 double knock-out mice
Molecular Psychiatry·2021· 40 citedOpen Access
From Synaptic Dysfunction to Neuroprotective Strategies in Genetic Parkinson’s Disease: Lessons From LRRK2
Frontiers in Cellular Neuroscience·2020· 20 citedOpen Access
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Frequent Co-authors

Cinzia Costa(18), Alessandro Tozzi(14), Emilia Castigli(14), Laura Bellingacci(12), Sergio Fucile(11), Alfredo Megaro(10), Paolo Calabresi(10), Massimiliano Di Filippo(9), Andrea Mancini(8), Petra Mazzocchetti(7), Bernard Fioretti(6), Fabio Franciolini(6), Lucilla Parnetti(6), Cecilia Gotti(6), Luigi Catacuzzeno(5), Luis Zafra‐Puerta(5), Nerea Iglesias‐Cabeza(5), Jacopo Canonichesi(5), Marina P. Sánchez(5), José M. Serratosa(5)