Grace O’Malley

Ollscoil na Gaillimhe – University of Galway — Ireland

Medicine · Health Sciences

8h-index456citations18works15.02yr avg
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Research Topics

Cancer Immunotherapy and Biomarkers(7), Immune cells in cancer(5), Mesenchymal stem cell research(4), Cancer Cells and Metastasis(4), Immunotherapy and Immune Responses(3)

Publications18 total

Tumor-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signaling
iScience·2024· 15 citedOpen Access
Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment
Cell Reports·2023· 84 citedOpen Access
In vivo Assessment of the Impact of Molecular Weight on Constructs of 68Ga-DOTA-Manocept in a Syngeneic Mouse Tumor Model
Molecular Imaging and Biology·2023· 1 citedOpen Access
Stromal cell sialylation suppresses T cells in inflammatory tumour microenvironments: A new tumour stromal cell immune checkpoint?
2021· 4 citedOpen Access
864 The mesenchymal stromal compartment in colorectal cancer greatly alters the innate tumour immune microenvironment both in 2D and 3D culture systems
2020· 2 citedOpen Access
TGF-β1-Licensed Murine MSCs Show Superior Therapeutic Efficacy in Modulating Corneal Allograft Immune Rejection In Vivo
Molecular Therapy·2020· 67 citedOpen Access
Mesenchymal Stromal Cell Sialylation Modulates Antitumor Immune Responses In Multiple Myeloma
Clinical Lymphoma Myeloma & Leukemia·2019· 1 cited
Stromal Cell PD-L1 Inhibits CD8+ T-cell Antitumor Immune Responses and Promotes Colon Cancer
Cancer Immunology Research·2018· 107 cited
Cellular interactions in the tumour microenvironment during inflammation-associated carcinogenesis
ARAN (University of Galway Research Repository) (Ollscoil na Gaillimhe – University of Galway)·2017Open Access
Abstract 2693: Inflammatory signalling in the colon tumour microenvironment enhances stromal cell mediated suppression of anti-tumour immune responses
Cancer Research·2017
Extracellular vesicles derived from human mesenchymal stem cells promote corneal wound repair by increasing epithelial cell proliferation and reducing neovascularisation in a rat corneal alkali burn model
2016
Mesenchymal stromal cells (MSCs) and colorectal cancer: a troublesome twosome for the anti-tumour immune response?
Oncotarget·2016· 70 citedOpen Access
Extracellular Vesicles Derived From Mesenchymal Stem Cells for Treatment of Ocular Surface Injuries
The FASEB Journal·2016· 1 cited
Evaluation of the Early In Vivo Response of a Functionally Graded Macroporous Scaffold in an Osteochondral Defect in a Rabbit Model
Annals of Biomedical Engineering·2015· 16 cited
Mesenchymal stem cell-derived extracellular vesicles promote corneal wound repair
Investigative Ophthalmology & Visual Science·2015
Evaluation of Cartilage Repair by Mesenchymal Stem Cells Seeded on a PEOT/PBT Scaffold in an Osteochondral Defect
Annals of Biomedical Engineering·2015· 32 citedOpen Access
Targeting colon cancer cell NF-κB promotes an anti-tumour M1-like macrophage phenotype and inhibits peritoneal metastasis
Oncogene·2014· 56 cited
Natural resistance to multiple tuberculous lesions
British Journal of Tuberculosis and Diseases of the Chest·1952

Frequent Co-authors

Aideen E. Ryan(13), Thomas Ritter(12), Oliver Treacy(8), Laurence J. Egan(8), Kevin Lynch(6), Niamh Leonard(6), Paul Lohan(6), Hannah Egan(5), Serika D. Naicker(4), Philip D. Dunne(4), Sweta Rani(4), Matthew D. Griffin(4), Kim De Veirman(3), Aisling Hogan(3), Keara L. Redmond(3), Mary C. Sheehan(3), Aoife Canney(3), Seán O. Hynes(3), Michael O’Dwyer(3), Eileen Reidy(2)