Aideen E. Ryan

Science Foundation Ireland — Ireland

Medicine · Health Sciences

32h-index4.5kcitations140works1.92yr avg
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Research Topics

Mesenchymal stem cell research(38), Cancer Immunotherapy and Biomarkers(19), Extracellular vesicles in disease(19), Corneal Surgery and Treatments(17), Cancer Cells and Metastasis(15)

Publications140 total

Phase 1b study of cyclophosphamide, pomalidomide, dexamethasone, and daratumumab (CPD-DARA) in relapsed/refractory multiple myeloma: Safety and efficacy in a heavily pretreated population
Blood·2025Open Access
1214 Understanding the mechanism of cancer-associated fibroblast subpopulation mediated immunomodulation in colorectal cancer
Regular and Young Investigator Award Abstracts·2025Open Access
1276 Targeting sialic acid on cancer-associated stromal cells modulates macrophage phenotype and phagocytosis in colorectal cancer
Regular and Young Investigator Award Abstracts·2025Open Access
813 Exploring the immunomodulatory role of extracellular vesicles on NK cells in stroma dense colorectal tumours
Regular and Young Investigator Award Abstracts·2025Open Access
Stromal cells modulate innate immune cell phenotype and function in colorectal cancer via the Sialic acid/Siglec axis
Journal for ImmunoTherapy of Cancer·2025· 1 citedOpen Access
Correction: Small extracellular vesicles secreted from TGF-β1-licensed mesenchymal stromal cells reduce inflammation-associated injury following corneal alkali burn
Stem Cell Research & Therapy·2025Open Access
Turning the tide in peritoneal metastases: Locoregional CAR-NK therapy primes systemic immunity in colorectal cancer
Molecular Therapy·2025Open Access
Small extracellular vesicles secreted from TGF-β1-licensed mesenchymal stromal cells reduce inflammation-associated injury following corneal alkali burn
Stem Cell Research & Therapy·2025· 1 citedOpen Access
In-vitro immunomodulatory efficacy of extracellular vesicles derived from TGF-β1/IFN-γ dual licensed human bone marrow mesenchymal stromal cells
Stem Cell Research & Therapy·2025· 3 citedOpen Access
The Tumour Glyco‐Code: Sialylation as a Mediator of Stromal Cell Immunosuppression in the Tumour Microenvironment
European Journal of Immunology·2025· 3 citedOpen Access
Identification of disease-stage therapeutic responses of mesenchymal stromal cells retrieved from murine osteoarthritic joints
Frontiers in Cell and Developmental Biology·2025· 1 citedOpen Access
Comparison of in-vitro immunomodulatory capacity between large and small apoptotic bodies from human bone marrow mesenchymal stromal cells
International Immunopharmacology·2025· 2 citedOpen Access
Stromal cells modulate innate immune cell phenotype and function in colorectal cancer via the Sialic acid/Siglec axis
2025· 1 citedOpen Access
AB078. SOH25_AB_135. Extracellular vesicles in colorectal cancer: drivers of CMS4 tumour-induced immune modulation and potential biomarkers
Mesentery and Peritoneum·2025Open Access
AB081. SOH25_AB_252. Cancer-associated fibroblasts modulate immune cell function via sialic acid-siglec axis in colorectal cancer
Mesentery and Peritoneum·2025Open Access
Investigation of immune response to Mesenchymal Stromal Cell-derived Extracellular Vesicles in the cancer setting
2025Open Access
Comparison of In-Vitro Immunomodulatory Capacity between Large and Small Apoptotic Bodies from Human Bone Marrow Mesenchymal Stromal Cells
SSRN Electronic Journal·2025Open Access
Encapsulation of msc‐derived extracellular vesicles in biomaterials for effective drug delivery to the ocular surface
Acta Ophthalmologica·2025
Dual gene set enrichment analysis (dualGSEA); an R function that enables more robust biological discovery and pre-clinical model alignment from transcriptomics data
Scientific Reports·2024· 6 citedOpen Access
Viral mimicry redirects immunosuppressed colorectal tumour landscapes towards a proinflammatory and CMS1-like regenerative state
2024Open Access
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Frequent Co-authors

Thomas Ritter(23), Oliver Treacy(17), Paul Lohan(14), Matthew D. Griffin(12), Kevin Lynch(9), Laurence J. Egan(8), Niamh Leonard(7), Mary Murphy(7), Frank Barry(6), Grace O’Malley(6), Lisa O’Flynn(6), Aileen Houston(6), Philip D. Dunne(5), Michael O’Dwyer(5), Sharon A. Glynn(4), Serika D. Naicker(4), Fergus Shanahan(4), Joe O’Connell(4), Eileen Reidy(4), Maurice Morcos(4)