Lisa O’Flynn

22q11 Ireland — Ireland

Medicine · Health Sciences

15h-index1.5kcitations45works1.32yr avg
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Research Topics

Mesenchymal stem cell research(22), Corneal Surgery and Treatments(12), Tissue Engineering and Regenerative Medicine(9), Immunotherapy and Immune Responses(7), Neonatal Respiratory Health Research(5)

Publications45 total

Efficient Non-Invasive Delivery of RNA for Somatic Reprogramming of Blood-derived cells
Cytotherapy·2025
A scalable, rapid and automated manufacturing platform, Solupore®, a flexible offering for both autologous and allogeneic cell therapies.
Cytotherapy·2025
Increased functional potency of multi-edited CAR-T cells manufactured by a non-viral transfection system
Molecular Therapy — Methods & Clinical Development·2024· 5 citedOpen Access
MULTI GENE EDITING OF IPSCS WITH NOVEL TRANSFECTION PLATFORM SOLUPORE® FOR GENERATION OF EFFICIENTLY EDITED AND HEALTHY IPSC LINES.
Cytotherapy·2024
Nutrition in decompensated liver disease: A regional trainee-led audit investigating patient nutrition and outcomes following admission with decompensated chronic liver disease
Clinical Nutrition ESPEN·2022
Impact of Syndecan-2-Selected Mesenchymal Stromal Cells on the Early Onset of Diabetic Cardiomyopathy in Diabetic db/db Mice
Frontiers in Cardiovascular Medicine·2021· 8 citedOpen Access
Non-viral clinical-scale engineering of T cells in an automated and functionally closed system
Cytotherapy·2021
Bone marrow stromal cell transplantation ameliorates cytopenia caused by depletion FAP-α expressing cells
2020Open Access
Targeting stromal cell Syndecan‐2 reduces breast tumour growth, metastasis and limits immune evasion
International Journal of Cancer·2020· 64 citedOpen Access
MALDI‐IMS as a Tool to Determine the Myocardial Response to Syndecan‐2‐Selected Mesenchymal Stromal Cell Application in an Experimental Model of Diabetic Cardiomyopathy
PROTEOMICS - CLINICAL APPLICATIONS·2020· 12 citedOpen Access
Administration of Human Non-Diabetic Mesenchymal Stromal Cells to a Murine Model of Diabetic Fracture Repair: A Pilot Study
Cells·2020· 5 citedOpen Access
Umbilical cord-derived CD362+ mesenchymal stromal cells for E. coli pneumonia: impact of dose regimen, passage, cryopreservation, and antibiotic therapy
Stem Cell Research & Therapy·2020· 44 citedOpen Access
Additional file 1 of Umbilical cord-derived CD362+ mesenchymal stromal cells for E. coli pneumonia: impact of dose regimen, passage, cryopreservation, and antibiotic therapy
Figshare·2020Open Access
THU-079-Study of anti-fibrotic activity of human umbilical-cord tissue-derived mesenchymal stromal cells during fibrogenesis or resolution in murine models of liver fibrosis
Journal of Hepatology·2019
Syndecan-2–positive, Bone Marrow–derived Human Mesenchymal Stromal Cells Attenuate Bacterial-induced Acute Lung Injury and Enhance Resolution of Ventilator-induced Lung Injury in Rats
Anesthesiology·2018· 52 cited
Monocytic Cells Phagocytose Therapeutic Mesenchymal Stem Cells, which Induces Polarization, Relocation and Immune Regulation
Transplantation·2018
Epigenetic changes in umbilical cord mesenchymal stromal cells upon stimulation and culture expansion
Cytotherapy·2018· 28 cited
Sub-cutaneously delivered mesenchymal stromal cells and down-regulation of activated vascular endothelium – a novel, clinically ready, therapeutic approach to treating cholestatic liver disease
Journal of Hepatology·2018
Cell therapy for acute liver injury- in vivo efficacy of mesenchymal stromal cells in toxic and immune-mediated murine hepatitis
Journal of Hepatology·2018Open Access
Immunomodulation By Therapeutic Mesenchymal Stromal Cells (MSC) Is Triggered Through Phagocytosis of MSC By Monocytic Cells
Stem Cells·2018· 503 citedOpen Access
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Frequent Co-authors

Thomas Ritter(16), Oliver Treacy(15), Aideen E. Ryan(14), Steve Elliman(10), Timothy O’Brien(10), Mourice Morcos(10), Mikhail Nosov(9), Philip N. Newsome(8), Paul Loftus(8), Stephen J. Elliman(8), Marese Cregg(8), Carla C. Baan(7), Martin J. Hoogduijn(7), Mieszko M. Wilk(7), S Witte(5), Ana Merino(5), Debashish Roy(5), Sabine Schu(5), Frank Barry(5), Paul Lohan(5)