Hussein Al‐Mossawi

AstraZeneca (United Kingdom) — United Kingdom

Medicine · Health Sciences

21h-index2.2kcitations106works6.92yr avg
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Research Topics

Spondyloarthritis Studies and Treatments(32), Psoriasis: Treatment and Pathogenesis(28), Systemic Lupus Erythematosus Research(26), Autoimmune and Inflammatory Disorders Research(21), Rheumatoid Arthritis Research and Therapies(15)

Publications106 total

Inhibition of cell-mediated immunity in type 1 diabetes by beta cell-targeted PD-1 agonists in pancreas tissue slices
2025Open Access
Metabolomic profiling of patients with lupus nephritis reveals unique metabolites that are modulated through type I interferon inhibition by anifrolumab treatment in a phase 2 trial
RMD Open·2025Open Access
Genetic determinants of monocyte splicing are enriched for disease susceptibility loci
Nature Communications·2025Open Access
Cell-targeted PD-1 agonists are potent NK-cell inhibitors
Frontiers in Immunology·2025· 1 citedOpen Access
0046 CD1a-targeted PD-1 agonists for localized immunosuppression in atopic dermatitis
Journal of Investigative Dermatology·2025Open Access
Reassessing antimalarial use in long-term SLE clinical trials – Authors' reply
The Lancet Rheumatology·2025· 1 cited
Synovial tissue atlas in juvenile idiopathic arthritis reveals pathogenic niches associated with disease severity
Science Translational Medicine·2025· 12 citedOpen Access
High prevalence of MASLD in psoriasis and psoriatic arthritis assessed with multiparametric magnetic resonance imaging
Lara D. Veeken·2025Open Access
Long-term effect of anifrolumab on patient-reported outcomes in systemic lupus erythematosus (TULIP-LTE): a randomised, placebo-controlled, phase 3 long-term extension trial
The Lancet Rheumatology·2025· 6 cited
E102 Transcriptomic effects of methotrexate on natural killer cells in psoriatic arthritis
Lara D. Veeken·2025Open Access
Liver fibro-inflammation in psoriatic arthritis with MASLD improved by anti-IL-17 treatment: a clinical case
Lara D. Veeken·2025Open Access
LLDAS and remission attainment with anifrolumab treatment in patients with systemic lupus erythematosus: results from the TULIP and long-term extension randomised controlled trials
Annals of the Rheumatic Diseases·2025· 13 citedOpen Access
A randomised, parallel-group, double-blind, placebo-controlled phase 3 study to Determine the effectiveness of the type I interferon receptor antibody, Anifrolumab, In SYstemic sclerosis: DAISY study design and rationale
Clinical and Experimental Rheumatology·2024· 12 citedOpen Access
Publisher Correction: Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus
Nature·2024· 4 citedOpen Access
Genetic determinants of monocyte splicing are enriched for disease susceptibility loci including for COVID-19
2024Open Access
Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus
Nature·2024· 68 citedOpen Access
Granulocyte-macrophage colony-stimulating factor neutralisation in patients with axial spondyloarthritis in the UK (NAMASTE): a randomised, double-blind, placebo-controlled, phase 2 trial
The Lancet Rheumatology·2024· 10 citedOpen Access
Correction: Targeting DORIS Remission and LLDAS in SLE: A Review
Rheumatology and Therapy·2024· 1 citedOpen Access
POS0024 IMPROVEMENT OF HEMATOLOGICAL PARAMETERS DURING LONG-TERM ANIFROLUMAB TREATMENT AND ASSOCIATION WITH WEEK 52 BICLA RESPONSE
Annals of the Rheumatic Diseases·2024· 1 cited
AB0435 HIGH PREVALENCE OF LIVER DISEASE ACTIVITY IN PSORIATIC ARTHRITIS AND PSORIASIS AFTER CONTROLLING FOR OBESITY, IDENTIFIED BY QUANTITATIVE MAGNETIC RESONANCE IMAGING
Annals of the Rheumatic Diseases·2024· 1 cited
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Frequent Co-authors

Paul Bowness(22), Jelle de Wit(10), Eric F. Morand(8), Julian C. Knight(7), Nicole Yager(7), Raj Tummala(7), Anna Ridley(7), Ariane Hammitzsch(6), Davide Simone(6), Kenneth Kalunian(6), Richard Furie(6), Gabriel Abreu(6), Catharina Lindholm(6), Benjamin P. Fairfax(5), Frank Penkava(5), Anne J. Ridley(5), Ronald van Vollenhoven(5), Kimme L Hyrich(5), Chelsea Taylor(4), Isar Nassiri(4)