Juan Carlos Gómora

Instituto Nacional de Cardiología — Mexico

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index2.2kcitations55works5.02yr avg
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Research Topics

Ion channel regulation and function(47), Cardiac electrophysiology and arrhythmias(25), Neuroscience and Neuropharmacology Research(21), Nicotinic Acetylcholine Receptors Study(17), Neuroscience and Neural Engineering(10)

Publications55 total

Design, Synthesis, and Evaluation of Sodium Channel Blockers with Anti-invasive Activities in Medullary Thyroid Cancer
ACS Medicinal Chemistry Letters·2025· 1 cited
Blockade of Ca<sub>V</sub>3 calcium channels and induction of G<sub>0</sub>/G<sub>1</sub> cell cycle arrest in colon cancer cells by gossypol
British Journal of Pharmacology·2024· 6 citedOpen Access
Therapeutic targeting of voltage-gated sodium channel NaV1.7 for cancer metastasis
Frontiers in Pharmacology·2024· 8 citedOpen Access
Voltage-gated sodium channels: from roles and mechanisms in the metastatic cell behavior to clinical potential as therapeutic targets
Frontiers in Pharmacology·2023· 26 citedOpen Access
Voltage-Gated Sodium Channel NaV1.7 Inhibitors with Potent Anticancer Activities in Medullary Thyroid Cancer Cells
Cancers·2023· 12 citedOpen Access
Effect of the Ketone Body, D-β-Hydroxybutyrate, on Sirtuin2-Mediated Regulation of Mitochondrial Quality Control and the Autophagy–Lysosomal Pathway
Cells·2023· 58 citedOpen Access
The T-1 conotoxin μ-SrVA from the worm hunting marine snail Conus spurius preferentially blocks the human NaV1.5 channel
Peptides·2022· 2 cited
Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers
iScience·2021· 42 citedOpen Access
Interaction of MDIMP with the Voltage-Gated Calcium Channels
Molecular Pharmacology·2020Open Access
Contribution of voltage-gated sodium channel β-subunits to cervical cancer cells metastatic behavior
Cancer Cell International·2019· 26 citedOpen Access
Pore-Blocking Effect of Isoindoline MDIMP on Voltage-Gated Calcium Channels
Biophysical Journal·2019· 1 citedOpen Access
Increase of CaV3 channel activity induced by HVA β1b-subunit is not mediated by a physical interaction
BMC Research Notes·2018· 5 citedOpen Access
The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity
Scientific Reports·2018· 47 citedOpen Access
Contribution of S4 segments and S4-S5 linkers to the low-voltage activation properties of T-type CaV3.3 channels
PLoS ONE·2018· 4 citedOpen Access
Block of Recombinant T-Type Calcium Channels by Gossypol, a Potential Contraceptive
Biophysical Journal·2016· 2 citedOpen Access
Blocking of T-Type Calcium Channels by TTA-A2 Reveals a Conservative Binding Site for State-Dependent Antagonists
Biophysical Journal·2016· 3 citedOpen Access
CDKN3 mRNA as a Biomarker for Survival and Therapeutic Target in Cervical Cancer
PLoS ONE·2015· 40 citedOpen Access
Novel TASK channels inhibitors derived from dihydropyrrolo[2,1-a]isoquinoline
Neuropharmacology·2013· 11 cited
Insulin-mediated upregulation of T-type Ca2+ currents in GH3 cells is mediated by increased endosomal recycling and incorporation of surface membrane Cav3.1 channels
Cell Calcium·2012· 8 cited
Block of Human CaV3 Channels by the Diuretic Amiloride
Molecular Pharmacology·2012· 9 cited
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Frequent Co-authors

Edward Perez‐Reyes(10), John J. Enyeart(9), Osbaldo Lopez‐Charcas(7), Judith A. Enyeart(7), Jung‐Ha Lee(5), Manuel Rivera(5), Ricardo Felix(5), Sadanandan E. Velu(5), Ana Laura Sánchez-Sandoval(5), Asif N. Daud(4), Dulce Marı́a Delgadillo(4), Jaime Berúmen(4), Ana Alfaro(4), Zazil Herrera‐Carrillo(4), Piyasuda Pukkanasut(4), Leanne L. Cribbs(3), Alberto Darszon(3), Alejandro Sandoval(3), Lin Xu(3), Guillermo Ávila(3)