Akaitz Dorronsoro

Centro Andaluz de Biología Molecular y Medicina Regenerativa — Spain

Medicine · Health Sciences

20h-index4.4kcitations36works8.02yr avg
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Research Topics

Mesenchymal stem cell research(10), Extracellular vesicles in disease(9), MicroRNA in disease regulation(7), Telomeres, Telomerase, and Senescence(5), Tissue Engineering and Regenerative Medicine(5)

Publications36 total

LRH‐1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype
Clinical and Translational Medicine·2024· 8 citedOpen Access
LRH-1/NR5A2 Activation Rewires Immunometabolism Blunting Inflammatory Immune Cell Progression in Individuals with Type 1 Diabetes and Enhances Human Islet Function in Mice
2023Open Access
Dietary fatty acids and endometrial cancer risk within the European Prospective Investigation into Cancer and Nutrition
BMC Cancer·2023· 4 citedOpen Access
MicroRNA-4732-3p Is Dysregulated in Breast Cancer Patients with Cardiotoxicity, and Its Therapeutic Delivery Protects the Heart from Doxorubicin-Induced Oxidative Stress in Rats
Antioxidants·2022· 20 citedOpen Access
NR5A2/LRH-1 regulates the PTGS2-PGE2-PTGER1 pathway contributing to pancreatic islet survival and function
iScience·2022· 25 citedOpen Access
Defects in Long-Term APC Repopulation Ability of Adult Human Bone Marrow Hematopoietic Stem Cells (HSCs) Compared with Fetal Liver HSCs
The Journal of Immunology·2022· 4 citedOpen Access
Corrigendum to “Plasmatic Membrane Expression of Adhesion Molecules in Human Cardiac Progenitor/Stem Cells Might Explain Their Superior Cell Engraftment after Cell Transplantation”
Stem Cells International·2022Open Access
HIF-Overexpression and Pro-Inflammatory Priming in Human Mesenchymal Stromal Cells Improves the Healing Properties of Extracellular Vesicles in Experimental Crohn’s Disease
International Journal of Molecular Sciences·2021· 73 citedOpen Access
miR-4732-3p in Extracellular Vesicles From Mesenchymal Stromal Cells Is Cardioprotective During Myocardial Ischemia
Frontiers in Cell and Developmental Biology·2021· 49 citedOpen Access
HIF-1α and Pro-Inflammatory Signaling Improves the Immunomodulatory Activity of MSC-Derived Extracellular Vesicles
International Journal of Molecular Sciences·2021· 56 citedOpen Access
Mesenchymal stem cell‐derived extracellular vesicles reduce senescence and extend health span in mouse models of aging
Aging Cell·2021· 140 citedOpen Access
Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation
Scientific Reports·2020· 82 citedOpen Access
Mesenchymal stem cell-derived extracellular vesicles reduce senescence and extend healthspan in mouse models of aging.
Zenodo (CERN European Organization for Nuclear Research)·2020Open Access
Mesenchymal stem cell-derived extracellular vesicles reduce senescence and extend healthspan in mouse models of aging.
Aging Cell·2020Open Access
Plasmatic Membrane Expression of Adhesion Molecules in Human Cardiac Progenitor/Stem Cells Might Explain Their Superior Cell Engraftment after Cell Transplantation
Stem Cells International·2020· 10 citedOpen Access
Extracellular Vesicles Secreted by Hypoxic AC10 Cardiomyocytes Modulate Fibroblast Cell Motility
Frontiers in Cardiovascular Medicine·2018· 21 citedOpen Access
Identification of HSP90 inhibitors as a novel class of senolytics
Nature Communications·2017· 653 citedOpen Access
Inhibition of NF-κB improves the stress resistance and myogenic differentiation of MDSPCs isolated from naturally aged mice
PLoS ONE·2017· 10 citedOpen Access
IFNγ Regulates Activated Vδ2+ T Cells through a Feedback Mechanism Mediated by Mesenchymal Stem Cells
PLoS ONE·2017· 7 citedOpen Access
Quantitative Analysis of Cellular Senescence in Culture and In Vivo
Current Protocols in Cytometry·2017· 20 cited
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Frequent Co-authors

Pilar Sepúlveda(13), César Trigueros(11), Paul D. Robbins(9), Laura J. Niedernhofer(7), Jon Fernández‐Rueda(7), Izaskun Ferrin(6), Sara J. McGowan(5), Emma Jakobsson(5), Robert W. Brooks(4), Diego Grassi(4), Lana Corbo(4), Francisco García‐García(4), Donna B. Stolz(4), Johnny Huard(4), Juan Manuel Salcedo(4), Karoline Fechter(4), Marta Gómez-Ferrer(4), Rafael Sánchez-Sánchez(4), Imelda Ontoria‐Oviedo(4), António Bernad(4)