Laura J. Niedernhofer

University of Minnesota — United States

Medicine · Health Sciences

79h-index30.0kcitations301works13.12yr avg
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Research Topics

Telomeres, Telomerase, and Senescence(80), DNA Repair Mechanisms(68), Genetics, Aging, and Longevity in Model Organisms(57), Spine and Intervertebral Disc Pathology(20), DNA and Nucleic Acid Chemistry(18)

Publications300 total

Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice
Cell Metabolism·2025· 3 cited
Distinct senotypes in p16- and p21-positive cells across human and mouse aging tissues
The EMBO Journal·2025· 4 citedOpen Access
Comprehensive healthspan assessments and influence of sex as a biological variable in aging rats
2025Open Access
Author Correction: Clonal dynamics and somatic evolution of haematopoiesis in mouse
Nature·2025Open Access
Advancing biological understanding of cellular senescence with computational multiomics
Nature Genetics·2025· 10 citedOpen Access
Lymphoma accelerates T cell and tissue aging
Cancer Cell·2025· 2 citedOpen Access
Liver Tissue Tissue Microarray (TMA) Embedding and Sectioning --University of Minnesota TMCs v1
2025Open Access
Uniquely high spontaneous mutational load in blood cells of XP-C patients
2025Open Access
Additional Cover
Aging Cell·2025Open Access
UMN-TMCs: CosMx Spatial Molecular Imager for FFPE Tissue – RNA 1K-Plex (v2) v1
2025Open Access
Fucoidans are senotherapeutics that enhance SIRT6-dependent DNA repair
2025· 1 citedOpen Access
Fucoidans are senotherapeutics that enhance SIRT6-dependent DNA repair
2025Open Access
Identification of Senomorphic <scp>miRNAs</scp> in Embryonic Progenitor and Adult Stem Cell‐Derived Extracellular Vesicles
Aging Cell·2025· 1 citedOpen Access
UMN-TMCs: CosMx Spatial Molecular Imager for FFPE Tissue – RNA 1K-Plex (v1) v1
2025Open Access
Accelerating the promise of geroscience through The Academy of Health &amp; Lifespan Research
Nature Aging·2025
Clonal dynamics and somatic evolution of haematopoiesis in mouse
Nature·2025· 22 citedOpen Access
Symposia Report of The Annual Biological Sciences Section Meeting of the Gerontological Society of America 2023, Tampa, Florida
The Journals of Gerontology Series A·2025Open Access
A brief report on biomarkers of cellular senescence associated with liver frailty and length of stay in liver transplantation
GeroScience·2024· 4 citedOpen Access
Activated Interferon Signaling Suppresses Age-Dependent Liver Cancer
2024Open Access
Nuclei isolation from human frozen adipose tissue for single-nuclei RNA-sequence. Adapted from three published articles. v2
2024Open Access
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Frequent Co-authors

Paul D. Robbins(30), James L. Kirkland(14), Tamar Tchkonia(12), Jan H.J. Hoeijmakers(10), Yi Zhu(9), Andria R. Robinson(8), Sundeep Khosla(7), Sara J. McGowan(7), Matthew J. Yousefzadeh(7), Yinsheng Wang(7), Diana Jurk(6), Tamar Pirtskhalava(6), Heike Fuhrmann‐Stroissnigg(6), João F. Passos(5), Nino Giorgadze(5), Nathan K. LeBrasseur(5), Cheryl L. Clauson(5), Judith Campisi(4), Aditi U. Gurkar(4), Luise Angelini(4)