Tamar Tchkonia

Cedars-Sinai Medical Center — United States

Medicine · Health Sciences

93h-index47.8kcitations340works10.72yr avg
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Research Topics

Telomeres, Telomerase, and Senescence(130), Adipokines, Inflammation, and Metabolic Diseases(56), Adipose Tissue and Metabolism(46), Glioma Diagnosis and Treatment(40), Genetics, Aging, and Longevity in Model Organisms(39)

Publications336 total

Early and Late Myocardial Effects of Proton Beam Cardiac Radioablation
JACC. Clinical electrophysiology·2025· 1 cited
Space radiation induces distinct senescent phenotypes: Implications for space travel
npj Aging·2025Open Access
Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice
Cell Metabolism·2025· 3 cited
Senotherapeutics for metabolic disease and diabetic complications
Journal of Internal Medicine·2025Open Access
The Role of Supraoptic Hypothalamic Arginine Vasopressin Neurons in Aging-Associated Water Balance and Thermoregulatory Deficits
2025Open Access
Abstract 4344658: Endothelial cell specific senescent cell clearance alleviates metabolic dysfunction in obese mice
Circulation·2025
Pharmacological clearance of senescent cells reduces inflammation, endothelial damage and cardiac fibrosis in HFpEF
Cardiovascular Research·2025· 1 citedOpen Access
Translating cellular senescence research into clinical practice for metabolic disease
Nature Reviews Endocrinology·2025· 1 cited
Effects of inhibition of Janus kinase signalling during controlled mechanical ventilation on the rate of skeletal muscle protein synthesis
The Journal of Physiology·2025· 1 citedOpen Access
Comprehensive healthspan assessments and influence of sex as a biological variable in aging rats
2025Open Access
Advancing biological understanding of cellular senescence with computational multiomics
Nature Genetics·2025· 10 citedOpen Access
Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers
2025Open Access
Cellular senescence promotes macrophage-to-myofibroblast transition in chronic ischemic renal disease
Cell Death and Disease·2025· 9 citedOpen Access
A human and mouse subpopulation of senescent β-cells induces pathologic dysfunction through targetable paracrine signaling
2025Open Access
Evaluation of exploratory fluid biomarkers from a phase 1 senolytic trial in mild Alzheimer’s disease
Neurotherapeutics·2025· 8 citedOpen Access
Senescence profiling of monoclonal gammopathies reveals paracrine senescence as a crucial defense against disease progression
Leukemia·2025· 2 citedOpen Access
Activin A Antagonism with Follistatin Reduces Kidney Fibrosis, Injury, and Cellular Senescence-Associated Inflammation in Murine Diabetic Kidney Disease
Kidney360·2025· 8 citedOpen Access
Senolytic Therapy in Chronic Spinal Cord Injury Promotes Functional Recovery and a Pro-Regenerative Glial Profile (Abstract ID: 190334)
Journal of Pharmacology and Experimental Therapeutics·2025
A pilot study of senolytics to improve cognition and mobility in older adults at risk for Alzheimer’s disease
EBioMedicine·2025· 38 citedOpen Access
SenSkin™: a human skin-specific cellular senescence gene set
GeroScience·2025· 4 citedOpen Access
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Frequent Co-authors

James L. Kirkland(49), Tamar Pirtskhalava(20), Nathan K. LeBrasseur(18), Yi Zhu(16), Nino Giorgadze(15), Paul D. Robbins(12), Laura J. Niedernhofer(11), Mikołaj Ogrodnik(11), Michael D. Jensen(11), Sundeep Khosla(10), Diana Jurk(10), Allyson K. Palmer(9), Ming Xu(9), Kurt O. Johnson(9), Larissa Prata(8), João F. Passos(8), Jordan D. Miller(7), Marissa J. Schafer(7), Joshua N. Farr(6), Michael B. Stout(6)