Joshua N. Farr

Mayo Clinic — United States

Medicine · Health Sciences

48h-index13.4kcitations138works6.52yr avg
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Research Topics

Telomeres, Telomerase, and Senescence(43), Bone health and osteoporosis research(41), Bone Metabolism and Diseases(24), Mesenchymal stem cell research(16), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(16)

Publications138 total

Senolytic Treatment Improves Responsiveness to Mechanical Loading in the Skeleton of Aged Mice
International Journal of Molecular Sciences·2025Open Access
SAT-311 Investigating the Effects of Non-Estrogenic Reproductive Hormones on Human Estrogen Receptor-Positive Breast Cancer Bone Metastases in a Murine Model
Journal of the Endocrine Society·2025Open Access
Comprehensive healthspan assessments and influence of sex as a biological variable in aging rats
2025Open Access
Towards a personalized approach in senolytic trials
Nature Aging·2025Open Access
Examination of Skeletal and Senescence Phenotypes in Young Mice with Juvenile Onset Type 1 Diabetes
Calcified Tissue International·2025Open Access
Biomarkers of Cellular Senescence in Type 2 Diabetes Mellitus
Aging Cell·2025· 5 citedOpen Access
Interrogating Steroid Hormone Signaling in a Murine Model of ER+ Human Breast Cancer Bone Metastases
Endocrinology·2025Open Access
Interrogating Steroid Hormone Signaling in a Murine Model of ER+ Human Breast Cancer Bone Metastases
Endocrinology·2025Open Access
Characterization of Human Senescent Cell Biomarkers for Clinical Trials
Aging Cell·2025· 10 citedOpen Access
Characterization of human senescent cell biomarkers for clinical trials
2024Open Access
6612 Both Overt And Mild Hypercortisolism Accelerate Biological Aging
Journal of the Endocrine Society·2024Open Access
Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial
Nature Medicine·2024· 68 citedOpen Access
Hdac3-deficiency increases senescence-associated distention of satellite DNA and telomere-associated foci in osteoprogenitor cells
Journal of Bone and Mineral Research·2024· 7 citedOpen Access
Marrow Adipocyte Senescence in the Pathogenesis of Bone Loss
Current Osteoporosis Reports·2024· 5 citedOpen Access
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair
Journal of Clinical Investigation·2024· 20 citedOpen Access
Cardiovascular Safety and Romosozumab—The Plot Thickens
The Journal of Clinical Endocrinology & Metabolism·2024· 4 citedOpen Access
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair
2024· 1 citedOpen Access
Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP
Nature·2024· 11 citedOpen Access
Contributors
Elsevier eBooks·2024
Age-related disease: Bones
Elsevier eBooks·2024
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Frequent Co-authors

Sundeep Khosla(40), David G. Monroe(21), James L. Kirkland(13), Tamar Tchkonia(12), Nathan K. LeBrasseur(12), Elizabeth J. Atkinson(12), Matthew T. Drake(9), Daniel G. Fraser(8), Madison L. Doolittle(8), Robert J. Pignolo(7), Dominik Saul(7), João F. Passos(7), Louise K. McCready(7), Jennifer L. Rowsey(7), Yuji Ikeno(6), Paul D. Robbins(6), Laura J. Niedernhofer(6), Megan Weivoda(6), Shreyasee Amin(6), Scott B. Going(6)