Brenda Aguilar

City Of Hope National Medical Center — United States

Medicine · Health Sciences

23h-index4.0kcitations117works19.22yr avg
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Research Topics

CAR-T cell therapy research(104), Immunotherapy and Immune Responses(37), Immune Cell Function and Interaction(17), Nanowire Synthesis and Applications(17), Viral Infectious Diseases and Gene Expression in Insects(9)

Publications117 total

TMOD-43. Development of Clinically Relevant Patient-Derived Brain Tumor Models for Advancing Therapeutic Evaluation
Neuro-Oncology·2025Open Access
Chlorotoxin-directed CAR T cell therapy for recurrent glioblastoma: Interim clinical experience demonstrating feasibility and safety
Cell Reports Medicine·2025· 3 citedOpen Access
Abstract 5279: Utilizing intravascular MHC-I antibody labeling to investigate regulation of tumor cell extravasation by ACKR1
Cancer Research·2025
Abstract 5285: Activation of endothelial ACKR1 in the pre-metastatic niche regulates neutrophil recruitment and tumor metastasis in breast cancer
Cancer Research·2025
Overcoming myeloid-driven resistance to CAR T therapy by targeting SPP1
2025· 3 citedOpen Access
Abstract A030: A deeper understanding of tumor microenvironment modulation induced by IL13Ra2 CAR T cells in a patient with grade 3 ependymoma
Cancer Immunology Research·2025
Abstract P015: Targeting SPP1 to enhance CAR T cell therapy in glioblastoma: Implications for integrating radiation therapy in resistant solid tumors
Clinical Cancer Research·2025
TMIC-42. CONQUERING SPP1+ MYELOID-DRIVEN RESISTANCE OF GLIOBLASTOMA TO IL13RA2-TARGETED CAR T CELL THERAPY
Neuro-Oncology·2024· 2 citedOpen Access
786 Evaluation of the immunomodulatory effects of radiation for chimeric antigen receptor T Cell therapy in glioblastoma multiforme
Regular and Young Investigator Award Abstracts·2024Open Access
Evaluation of the Immunomodulatory Effects of Radiation for Chimeric Antigen Receptor T Cell Therapy in Glioblastoma Multiforme
Cells·2024· 5 citedOpen Access
ENFERMEDAD DE KAWASAKI: MÁS ALLÁ DE LA FORMA CLÁSICA
2024
Author Correction: Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial
Nature Medicine·2024· 6 citedOpen Access
Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial
Nature Medicine·2024· 235 citedOpen Access
Targeting Wnt signaling for improved glioma immunotherapy
Frontiers in Immunology·2024· 15 citedOpen Access
580 Mapping interstitial fluid flow in the brain to improve CAR T cell trafficking and efficacy
Regular and Young Investigator Award Abstracts·2023Open Access
1520 Phase I trial evaluating locoregionally-delivered IL13Rα2-targeting CAR T cells in high-grade glioma
2023Open Access
1525 Initial clinical experience with chlorotoxin-redirected CAR T cells for patients with recurrent glioblastoma
2023· 2 citedOpen Access
IN33 MANAGEMENT OF A PATIENT WITH ADVANCED BREAST CANCER AND HIV
The Breast·2023Open Access
Phase I Trial Evaluating Locoregionally-delivered IL13Rα2-targeting CAR T Cells in High-Grade Glioma
2023· 1 citedOpen Access
Data from The Cerebroventricular Environment Modifies CAR T Cells for Potent Activity against Both Central Nervous System and Systemic Lymphoma
2023Open Access
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Frequent Co-authors

Christine E. Brown(43), Stephen J. Forman(37), Renate Starr(34), Behnam Badie(21), Julie R. Ostberg(18), Dongrui Wang(15), Michael C. Jensen(15), Michael E. Barish(14), Darya Alizadeh(13), Alfonso Brito(13), Wen-Chung Chang(12), Massimo D’Apuzzo(11), Jonathan Hibbard(10), Jamie R. Wagner(10), Xin Yang(9), Xiuli Wang(9), Robyn A. Wong(8), Aniee Sarkissian(8), Lihong Weng(7), Heini M. Natri(7)